Polyposis Syndrome Clinic
The Department of Hereditary and Preventive Medicine at Creighton University, in collaboration with the Department of Pediatrics at The University of Nebraska Medical Center offer a unique multidisciplinary clinical service including participation of a geneticist-oncologist, a genetic counselor, clinic RN and a pediatric gastroenterologist. The Department offers parents and physicians access to established expertise in the diagnosis and long-term management, including endoscopic surveillance of children with gastrointestinal polyps and polyposis syndromes including Familial Adenomatous Polyposis (FAP), Juvenile Polyposis Syndrome(JP), Peutz-Jeghers Syndrome (PJS) and PTEN-Hamartoma Syndrome including Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome (BRRS).
Since its inception in 2001 the Clinic has been involved in the care of over 100 children from over 50 families from throughout the United States; the group has been at the forefront in high-lighting the plight of individuals and families with polyposis with the pediatric and pediatric gastroenterology community. Accordingly the clinic experience has translated in several scientific-journal articles including research articles listed below.
Clinical evaluation usually entails a preliminary questionnaire to the parent(s) eliciting an extended family history that typically guides further, including genetic, testing. Children, along with their parents are usually seen by Dr Attard and by Dr Lynch together.
Genetic testing follows informed consent and assent from the child and a detailed description of the relevant findings is addressed to the referring physician including recommendations for continued surveillance in the family. The Clinic emphasizes the rational performance of genetic tests in the context of sensitivity to the psychosocial and economic impact of testing in children, a vulnerable population with unique needs.
Useful links and publications:
Iowa virtual Hospital - juvenile polyposis
Collaborative Group of the America
John Hopkins FAP resource
Attard & Lynch Practical Gastroenterology article (PDF)
Attard and Young Gastroenterology Nursing article (PDF)