Hereditary Cancer Center
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The History of HCC

The Hereditary Cancer Center (HCC) at Creighton University was established in 1984, with the financial help of a bequest.  The center's primary objective has been comprehensive research into hereditary cancer syndromes, with the goal of preventing cancer by enabling at-risk family members to receive targeted cancer screening and management of their cancer risk.  Particular emphasis has been on the hereditary breast ovarian cancer syndrome, the familial atypical multiple mole melanoma syndrome and its association with pancreatic cancer, and the hereditary nonpolyposis colorectal cancer syndrome, also referred to as Lynch syndrome.  As of 2006, HCC had accumulated a registry of 1743 families and more than 30,000 family members at risk for a variety of hereditary cancer syndromes.

HCC was established approximately a decade before medical science first gained the ability to discover specific mutations in human genes.  As that science has developed and genetic knowledge has expanded to require more and more specialized molecular research, HCC's commitment has evolved toward significantly increased collaboration with colleagues at Creighton as well as elsewhere.  HCC has helped in the development of educational hereditary cancer programs throughout the United States, and in areas of Canada, South America, Puerto Rico, Europe, and Asia.  In turn, collaborators from around the world have added their own resources and expertise to those of Creighton's in order to promote further research.