Welcome from the Chair
Welcome to our Departmental web pages. As you follow the various links you will find that the Department of Medical Microbiology and Immunology is involved in research and teaching that broadly relates to the dynamic interaction between microbial pathogenesis and host defense. In this context, Departmental expertise and interests include:
- mechanisms underlying the diversification of immune response
- virus-induced demyelination and the study of immune factors involved in the development of virus-associated pathology and clinical disease
- cellular response to microbial toxins
- the study of HIV and prion infectious processes
- animal models of immune defense against infection as influenced by ethanol comsumption and smoking
- molecular approaches to the epidemiological tracking of clinically-important pathogens
- genomic approaches to detecting problem microorganisms and understanding their mechanisms of pathogenesis
- animal models of infection and use of pharmacokinetic models to evaluate interactions between antimicrobial agents and bacteria
- molecular mechanisms of antibiotic resistance especially related to fluroquinolones and extended-spectrum beta-lactamases in clinical isolates
- the use of in vitro and in vivo approaches to evaluate the efficacy of new antimicrobial agents
Translational research in these areas has been a tradition in the Department for over 20 years and is facilitated by the potential for close interaction with infectious disease faculty who hold secondary appointments in the Department.
State of the art "core" facilities are available to support Department efforts. One of the most notable examples is our Flow Cytometry Core Facility which includes a Becton Dickinson FACSCalibur and a unique Becton Dickinson FACSAria configuration which can accomplish 3 laser, 12 parameter high speed sorting of up to 10 colors in 4 different populations simultaneously at up to 30,000 cells/second.
The Department of Medical Microbiology and Immunology is a growing and enthusiastic group of individuals (faculty, staff, post-docs, and students) working in an environment where a conscious effort is made to facilitate both individual and collective achievement. Our success in this area can be measured, in part, by the selected publications and presentations noted by faculty on their individual web pages referenced above.
Individuals desiring to know more about the Department are encouraged to contact us as indicated on the Department Information page.