Mohammed P. Akhter, PhD
Mohammed P. Akhter, PhD

Mohammed P. Akhter, PhD

Professor
School of Medicine

Academic Appointments

Department

  • Medicine

Position

  • Professor

Secondary Appointment

  • School of Dentistry

Education

  • NED University of Engineer & Technology,BS,1981
  • University of Nebraska,MS,1983
  • University of Nebraska-Lincoln,Ph.D.,1988

Publications and Presentations

Articles

  • S. Vennin,  A. Desyatova, J.A. Turner, P. Watson, J. Lappe, R.R. Recker,  M. P. Akhter. Intrinsic Material Property Differences in Bone Tissue from Patients Suffering Low-Trauma Osteoporotic Fractures, Compared to Matched Non-fracturing Women., Bone, 2017 Jan 27;97:233-242. PubMed PMID: 28132909., 2017
  • Akhter MP, Kimmel DB, Lappe JM, Recker RR (2016). Effect of Macroanatomic Bone Type and Estrogen Loss  on Osteocyte Lacunar Properties in Healthy Adult Women., Cacified Tissue International, 2017 Mar 1. doi: 10.1007/s00223-017-0247-6. [Epub ahead of print]., 2017
  • Aguirre JI, Akhter MP, Neuville KG, Trcalek CR, Leeper AM, Williams AA, Rivera M, Kesavalu L, Ke HZ, Liu M, Kimmel DB. Age-related periodontitis and alveolar bone loss in rice rats., Archives of Oral Biology, 2016 Oct 17;73:193-205. doi: 10.1016/j.archoralbio.2016.10.018. [Epub ahead of print], 2017
  • Farlay D, Armas LA, Gineyts E, Akhter MP, Recker RR, Boivin G. Nonenzymatic Glycation and Degree of Mineralization Are Higher in Bone From Fractured Patients With Type 1 Diabetes Mellitus. J Bone Miner Res. 2016 Jan;31(1):190-5. doi: 10.1002/jbmr.2607. Epub 2015 Sep 4. PubMed PMID: 26234180, Journal of Bone Mineral Research, 2016 Jan:31(1), 190-5, 2016
  • Feresin RG, Johnson SA, Elam ML, Kim JS, Khalil DA, Lucas EA, Smith BJ, Payton ME, Akhter MP, Arjmandi BH. Effects of vitamin E on bone biomechanical and histomorphometric parameters in ovariectomized rats. (2013). Journal of Osteoporosis [Epub 2013 Sep5, http://dx.doi.org/10.1155/2013/825985], Journal of Osteoporosis, 2013, 2013
  • Fang Yuan, Richard K. Nelson, Dana Tabor, Yijia Zhang, Mohammed P. Akhter, Karen A. Gould, Dong Wang (2012) Dexamethasone Prodrug Treatment Prevents Nephritis in Lupus-prone (NZBNZW) F1 Mice without Causing Systemic Side Effects. Arthritis Rheum. 2012 Dec;64(12):4029-39., Arthritis & Rheumatism, 64(12), 4029-39, 2012
  • Juma SS, Ezzat-Zadeh Z, Khalil DA, Hooshmand S, Akhter MP, Arjmandi BH. Soy protein with or without isoflavones failed to preserve bone density in gonadal hormone-deficient male rat model of osteoporosis (2012). Nutr Res. 2012 Sep;32(9):694-700. Epub 2012 Sep 23., Nutrition Research, 32(9), 694-700, 2012
  • Aguirre JI, Akhter MP, Kimmel DB, Pingel JE, Williams A, Jorgensen M, Kesavalu L, Wronski TJ (2012) Oncologic doses of zoledronic acid induce osteonecrosis of the jaw-like lesions in rice rats (Oryzomys Palustris) with periodontitis. J Bone Miner Res. 2012 May 23. doi: 10.1002/jbmr.1669. [Epub ahead of print], J Bone Miner Metab, 10, 1002, 2012
  • Ma D, Li Y, Hackfort B, Zhao Y, Xiao J, Swanson P, Lappe J, Xiao P, Cullen D, Akhter MP, Recker RR, Xiao GG (2012). Smoke-induced signal molecules in bone marrow cells from altered low-density lipoprotein receptor-related protein 5 mice. J Proteome Res. 2012 May 22. [Epub ahead of print]., Journal of Proteome Research, 11(7), 3548–3560, 2012
  • Polly BJ, Yuya PA, Akhter MP, Recker RR, Turner JA (2012) Intrinsic Material Properties of Trabecular Bone by Nanoindentation Testing of Biopsies Taken from Healthy Women Before and After Menopause. Calcif Tissue Int. 2012 Apr;90(4):286-93., Calcif Tissue Int, 90(4), 286-93, 2012
  • Aguirre JI, Akhter MP, Kimmel DB, Pingel J, Xia X, Williams A, Jorgensen M, Edmonds K, Lee JY, Reinhard MK, Battles AH, Kesavalu L, Wronski TJ. (2012) Enhanced alveolar bone loss in model of periodontitis in rice rats. Oral Dis. 2012 Jul;18(5):459-68. doi: 10.1111/j.1601-0825.2011.01893.x. Epub 2012 Jan 11., Oral Diseases, 18(5), 459-68, 2012
  • Armas LAG, Akhter MP, Drincic A, Recker RR (2011) Trabecular Bone Changes in Humans with Type 1 Diabetes Mellitus. Bone 50 (2012) 91–96., Bone, 50(2012), 91-96, 2012
  • Palmer VL, Kassmeier MD, Willcockson J, Akhter MP, Cullen DM,  Swanson P. N-acetylcysteine increases the frequency of bone marrow pro-B/pre-B cells, but does not reverse cigarette smoking-induced loss of this subset. PLoS One. 2011;6(9):e24804. Epub 2011 Sep 16., PLoS One, 6(9), e24804, 2011
  • Akhter MP, Alvarez GK, Cullen DM, Recker RR (2011) Disuse-related decline in trabecular bone structure. Biomech Model Mechanobiol. 2011 Jun;10(3):423-9. Epub 2010 Aug 4., Biomechanics and Modeling in Mechanobiology, 10(3), 423-9, 2011
  • Johnson CD, Lucas EA, Hooshmand S, Campbell S, Akhter MP, Arjmandi BH.. Addition of Fructooligosaccharides and Dried Plum to Soy-based Diets Reverses Bone Loss in the Ovariectomized Rat. Evid Based Complement Alternat Med. 2011., Journal of Evidence-Based Complementary & Alternative Medicine, 2011, 836267, 2011
  • Lopez Franco GE, Blank RD, Akhter MP. Intrinsic material properties of cortical bone. J Bone Miner Metab. 2011 Jan;29(1):31-6. doi: 10.1007/s00774-010-0194-z. Epub 2010 May 26. PubMed PMID: 20503060., J Bone Miner Metab, 1, 31-6, 2011
  • Fusby;Kassmeier;Palmer;Perry;Anderson;Hackfort;Alvarez;Cullen;AkhterMP;Swanson; (2010) Cigarette smoke-induced effects on bone marrow B cell subsets and CD4+:CD8+ T cell ratio are reversed by smoking cessation Influence of bone mass on immune cell response to and recovery from smoke exposure. Inhal Toxicol. 2010 Aug;22(9):785-96., Inhalation Toxicology, 22(9), 785-96, 2010
  • Manolides AS, Cullen DM, Akhter MP (2010) Effects of Glucocorticoid Treatment on Bone Strength. J Bone Miner Metab. 2010 Sep;28(5):532-9. Epub 2010 Jan 27, J Bone Miner Metab, 5, 532-9, 2010
  • Arjmandi BH, Johnson CD, Campbell SC, Hooshmand S, Chai SC, Akhter MP (2010). Combining fructooligosaccharide and dried plum has the greatest effect on restoring bone mineral density among select functional foods and bioactive compounds. J Med Food. 2010 Apr;13(2):312-9., Journal of Medicinal Food, 13(2), 312-9, 2010
  • Chipitsyna G, Gong Q, Anandanadesan R, Alnajar A, Batra SK, Wittel UA, Cullen DM, Akhter MP, Denhardt DT, Yeo CJ, Arafat HA.Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. Int J Cancer. 2009 Jul 15;125(2):276-85., Int. J. Cancer, 125(2), 276-85, 2009
  • Xin-Ming Liu, Andrew T. Wiswall, John E. Rutledge, Mohammed P. Akhter, Diane M. Cullen, Richard A. Reinhardt, Dong Wang. Osteotropic b-cyclodextrin for local bone regeneration. Biomaterials 29 (2008) 1686e1692., Biomaterials, 29(11), 1686-92, 2008
  • Kuruvilla S, Cullen DM, Akhter MP. Site Specific Bone Adaptation Response to Mechanical Loading. J Musculoskelet Neuronal Interact 2008; 8(1):71-78., J Musculoskeletal Neuronal Interact, 8(1), 71-78, 2008
  • Armas LAG, Dowell S, Akhter MP, Duthuluru S, Huerter C, Hollis BW, Lund R, Heaney RP (2007) Using UV-B light to raise serum Vitamin D levels.  Journal of the American Academy of Dermatology 57(4): 588-93., Journal of the American Academy of Dermatology, 57(4), 588-93, 2007
  • Akhter MP, Jung LKL (2007) Decreased Bone Strength in HLA-B27 transgenic rat model of Spondyloarthropathy.  Rheumatology-(Oxford). 2007 Aug; 46(8): 1258-62., Rheumatology (Oxford)., 46(8), 1258-62, 2007
  • Akhter MP Lappe JM, Davies KM, Recker RR (2007) Trans-menopausal Changes in the Trabecular Bone Structure. Bone. 2007 Jul; 41(1): 111-6., Bone, 4(1), 111-6, 2007
  • Dubrow SA, Hruby PM, Akhter MP (2007) LRP5 Increases Trabecular Bone Structure and Strength. J-Musculoskelet-Neuronal-Interact. 2007 Apr-Jun; 7(2): 166-73., J Musculoskeletal Neuronal Interact, 7(2), 166-73, 2007
  • Wittel UA, Singh AP, Henley BJ, Andrianifahanana M, Akhter MP, Cullen DM, Batra SK.. Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas. Pancreas. 2006 Nov;33(4):364-70., Pancreas, 33(4), 364-70, 2006
  • Robinson JA, Chatterjee-Kishore M, Yaworsky PJ, Cullen DM, Zhao W, Li C, Kharode Y, Sauter L, Babij P, Brown EL, Akhter MP, Johnson ML, Recker RR, Komm BS and Bex FJ (2006) Wnt/b-Catenin Signaling is a Normal Physiological Response to Mechanical Loading in Bone. The Journal of Biological Chemistry, Vol. 281, No. 42, pp. 31720–31728, October 20, 2006., J Biol Chem, vol 281 No 42, 31720-31728, 2006
  • Akhter MP, Cullen DM, Pan L (2006) Bone biomechanical properties in EP4 knock-out mice. Calcif Tissue Int (2006) 78:357-362., Calcif Tissue Int, 78, 357-362, 2006
  • Nandi S, Akhter MP, Seifert MF, Dai XM and Stanley ER (2006) Phenotypic differences between mice expressing secreted proteoglycan and glycoprotein isoforms of CSF-1. Blood 2006 107: 786-795., Blood, 107, 786-795, 2006
  • Wittel UA,. Pandey KK, Johansson SL, Cullen DM, Akhter MP, Brand RE, (2006) Prokopczyk B, and. Batra SK Chronic Pancreatic Inflammation Induced By Environmental Tobacco Smoke Inhalation In Rats. Am-J-Gastroenterol. 2006 Jan; 101(1): 148-59., Am J Gastroenterol, 101(1), 148-59, 2006
  • Akhter MP, Lund AD, Gairola CG (2005) Bone Biomechanical Property Deterioration Due to Tobacco Smoke Exposure. Calcified Tissue Int, 77 (5): 319-326 NOV 2005., Calcif Tissue Int, 77(5), 319-326, 2005
  • Khalil DA, Lucas EA, Smith BJ, Soung DY, Devareddy L, Juma S, Akhter MP, Recker R, Arjmandi BH Soy isoflavones may protect against orchidectomy-induced bone loss in aged male rats. Calcif-Tissue-Int., Calcif Tissue Int, 76(1), 56-62, 2005
  • Akhter MP, Fan Z, Rho JY Bone intrinsic material properties in three inbred mouse strains., Calcif Tissue Int, 75(5), 416-420, 2004
  • Dai XM, Zong XH, Akhter MP Stanley ER Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone., J. Bone Miner. Res., 19(9), 1441-1451, 2004
  • Akhter MP, Wells DJ, Short SJ, Cullen DM, Johnson ML, Haynatzki GR, Babij P, Allen KM, Yaworsky PJ, Bex F, Recker RR Bone biomechanical properties in LRP5 mutant mice., Bone, 35(1), 162-169, 2004
  • Akhter MP, Wells DJ, Short SJ, Cullen DM, Johnson ML, Haynatzki G, Babij P, Allen KM, Yaworsky PJ, Bex F, Recker RR Bone Biomechanical Properties in Lrp5 mutant mice (on-line punlication), Bone, 35, 162-169, 2004
  • Akhter MP, Otero JK, Iwaniec UT, Cullen DM, Recker RR Genetic (2004) Variation in Vertebral Biomechanics and Histomorphometry in Mice., J Musculoskeletal Neuronal Interact, 4(1): , 33-40, 2004
  • Akhter MP, Iwaniec UT, Haynatzki GR, Fung YK, Cullen DM, and Recker RR (2003) Effects of Nicotine on Bone Mass and Strength in Aged Female Rats., J. Ortho. Res., 21, 14-19, 2003
  • Arjmandi BH., Juma S, Beharka A, Bapna MS, Akhter MP, Simin, Meydani N (2002) Vitamin E: Evidence for its Role in Improving Bone Quality in the Ag, Journal of Nutrition, 13, 2002
  • Iwaniec UT, Fung YK, Haynatzki GR, Fung YK, Akhter MP, Haven, MC Cullen DM (2002) Effects of Nicotine on Bone and Calciotropic Hormones in Aged Ovariectomized Rats. Journal of Musculoskeletal and Neuronal Interactions 2(5) 469-478, J Musculoskeletal Neuronal Interact, 2(5), 469-478, 2002
  • Akhter MP, Cullen DM, Recker RR Breed related bone adaptation response to ex vivo sham and bending loads in mice, J Clinical Densitometry, vo. 5, n0. 2, 207-216, 2002
  • Akhter MP, Cullen DM, Recker RR (2002) Bone adaptation response to sham and bending stimuli in mice. J Clinical Densitometry, 5: 207-216., J Clinical Densitometry, 5, 207-216, 2002
  • Smith BJ, King JB, Lucas EA, Brusewitz G, Akhter MP, Arjmandi BH, Stoecker BJ (2002) Implications of skeletal unloading and dietary copper depletion on bone metabolism in mature rats. Journal of Nutrition Nutr. Feb; 132(2): 190-6., Journal of Nutrition, 132, 2, 190-6, 2002
  • Smith BJ, King JB, Lucas EA, Brusewitz G, Akhter MP, Arjmandi BH, Stoecker BJ Implications of skeletal unloading and dietary copper depletion on bone metabolism in mature rats, Journal of Nutrition, 132 (2), 190-6, 2002
  • Cullen DM, Smith RT, Akhter MP (2001) Bone-loading response varies with strain magnitude and cycle number. J Appl Physiol 91: 1971-1976., Journal of Applied Physiology, 91, 1971-1976, 2001
  • Akhter MP, Cullen DM, Gong G, Recker RR (2001) Bone Biomechanical Properties in Prostaglandin EP1 and EP2 Knock-out Mice., Bone, 29, 2, 121-125, 2001
  • Hagino H, Okano T, Akhter MP, Enokida M, Teshima R (2001) The Effect of Parathyroid Hormone on Cortical Bone Response to In Vivo External Loading. 19:244-250., Journal Bone Mineral Metabolism, 19, 244-250, 2001
  • Hagino H, Okano T, Akhter MP, Enokida M, Teshima R The Effect of Parathyroid Hormone on Cortical Bone Response to In Vivo External Loading, Journal Bone Mineral Metabolism, 19, 244-250, 2001
  • Iwaniec UT, Fung YK, Akhter MP, Haven MC, Nespor S, Haynatzki GR, Cullen DM Effects of nicotine on mineral desnity, histomorphometry, and strength in adult female rats. Calcif Tissue Int 68:358-364., Calcif Tissue Int, 68, 358-364, 2001
  • Samnegard E, Akhter MP. Recker RR (2001) Maintenance of Vertebral Body Bone Mass and Strength Created by hPTH Treatment in Ovariectomized Rats., Bone, 28, 4, 414-422, 2001
  • Samnegard E, Cullen DM, Akhter MP, Kimmel DB (2001) No effect of verapamil on bone response to in vivo mechanical loading., Journal of Orthopaedic Research, 19, 2, 328-336., 2001
  • Akhter MP, Cullen DM, Gong G, Recker RR (2001) Bone Biomechanical Properties in Prostaglandin EP1 and EP2 Knock-out Mice., Bone, 29, 2, 121-125, 2001
  • Akhter MP, Kimmel DB, Recker RR Effect of parathyroid hormone (hPTH[1-84]) treatment on bone mass and strength in ovariectomized rats., Journal of Clinical Densitometry, 4, 1, 13-23, 2001
  • Akhter MP, Iwaniec UT, Covey MA, Cullen DM, Kimmel DB, Recker RR (2000) Genetic variations in bone density, histomorphometry, and strength in mice., Calcif Tissue Int, 67, 337-49, 2000
  • Iwaniec UT, Fung YK, Cullen DM, Akhter MP, Haven MC, Schmid M (2000) Effects of Nicotine on Bone and Calciotropic Hormones in Growing Female Rats. Calcif Tissue Int 67:68-74., Calcif Tissue Int, 67, 68-74, 2000
  • Fung YK, Iwaniec UT, Cullen DM, Akhter MP, Haven MC, Timmins P., (1999) Long-term effects of nicotine and calciotropic hormones in adult female rats. Pharmacology & Toxicology vol. 85 (4):181-187)., Not Applicable, 1999
  • Pedersen EA, Akhter MP, Cullen DM, Kimmel DB, Recker RR (1999) Bone response to in vivo mechanical loading in mice. CTI 65.pp 41-46, Not Applicable, 1999
  • Turner CH, Akhter, MP,. (1999) Fatigue damage and strength. (Book chapter) (in press)., Not Applicable, 1999
  • Akhter MP, Otero JK, Iwaniec UT, Cullen DM, Recker RR Genetic (2002) Variation in Vertebral Biomechanics and Histomorphometry in Mice. J Ortho. Res (submitted).
  • Dai X, Zong X, Akhter MP, Stanley ER (2002) Essential role of osteoclast in normal bone formation during development. Nature (submitted).
  • Arjmandi BH., Juma S, Beharka A, Bapna MS, Akhter MP, Simin, Meydani N (2002) Vitamin E: Evidence for its Role in Improving Bone Quality in the Aged; J. Nutr. Biochemistry (In press).
  • Akhter MP, Iwaniec UT, Haynatzki GR, Fung YK, Cullen DM, and Recker RR (2002) Effects of Nicotine on Bone Mass and Strength in Aged Female Rats. J Orth. Res (in press).
  • Akhter MP, Otero JK, Iwaniec UT, Cullen DM, Recker RR Genetic (2003) Variation in Vertebral Biomechanics and Histomorphometry in Mice. CTI (submitted).
  • Akhter MP, Wells DJ, Short SJ, Cullen DM, Johnson ML, Haynatzki G, Babij P, Allen KM, Yaworsky PJ, Bex F, Recker RR Bone Biomechanical Properties in Lrp5 mutant mice (2003). JBMR (submitted).
  • Dai X, Zong X, Akhter MP, Stanley ER (2003) Essential role of osteoclast in normal bone formation during development. J Experimental Medicine (submitted).
  • Akhter MP, Rho JY, Fan F (2003) Genetic Regulation of Cortical Bone Intrinsic Properties In mice (submitted BONE).
  • Yee, JA, L Yan, D Cullen, M Akhter, RR Recker. Nicotine inhibits the differentiation and function of osteoblasts in cultures neonatal rat calvarial cells. Bone (Accepted with revision).
  • Wittel UA,. Pandey KK, Johansson SL, Cullen DM, Akhter MP, Brand RE, Prokopczyk B, and. Batra SK Chronic Pancreatic Inflammation Induced By Environmental Tobacco Smoke Inhalation In Rats. Submitted Am J Pathology 9/03.
  • Akhter MP, Lund AD, Gairola CG (2004) Tobacco Smoke Exposure and Bone Biomechanical Properties in Mice. CTI (submitted)
  • Akhter MP, Rho JY, Fan F (2004) Genetic Regulation of Cortical Bone Intrinsic Properties In mice CTI (accepted).
  • Moitreyee Chatterjee-Kishore, Paul J Yaworsky, Weiguong Zhao, John A Robinson, Christine Li, Yogendra Kharode, Eric Fortier, Linda Sauter, Michael Cain, Bheem Bhat, Melissa Wasko, Philip Babij, Ramesh Bhat, Peter V N Bodine, Eugene L Brown, Mark L Johnson, Mohammed P Akhter, Diane M Cullen, Robert R Recker and Frederick J Bex (2004) The anabolic response of bone to mechanical load involves the Wnt/ƒÒ¡Vcatenin pathway. JBMR(submitted).
  • Dai X, Zong X, Akhter MP, Stanley ER (2004) Osteoclast deficiency results in disorganized matrix, reduced mineralization and abnormal osteoblast behavior in developing bone. JBMR (in press).
  • Akhter MP, Lund AD, Gairola CG (2005) Bone Biomechanical Property Deterioration Due to Tobacco Smoke Exposure. (Calcified Tissue Int, in press).
  • Wittel, UA, Pandey KK, et al (2005) Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats. American Journal of Gastroenterology (in press).
  • Nandi S, Akhter MP, Seifert MF, Dai XM and Stanley ER (2005) Phenotypic differences between mice expressing secreted proteoglycan and glycoprotein isoforms of CSF-1. (Blood, in press).
    1. Yanzhi Liu; Zhenshan Jia; Mohammed P Akhter; Xiang, Gao; Xiaobei Wang; Xiaoyan Wang; Gang Zhao; Xin wei; Curtis W Hartman, Edward V Fehringer; Liao Cui; Dong Wang. Bone-targeting  Liposome Formulation of Salvianic Acid A Accelerates the Healing of Delayed Fracture Union in Mice.
    , Biomaterials
  • Aguirre JI, Edmonds K, Zamora B, Pingel J, Thomas L, Cancel D, Schneider L, Reinhard MK, Battles AH, Akhter MP, Kimmel DB, Wronski TJ. Breeding, husbandry, veterinary care, and hematology of marsh rice rats (Oryzomys palustris), a small animal model for periodontitis., J Am Assoc Lab Anim Sci., 2015 Jan;54(1), 51-8

Publications

  • Akhter MP, Cullen D, Gong G, Recker RR (1999) Biomechanical properties of bone in prostaglandin EP2 knockout mice. Othopaedic Research Society meeting (Abstract # 743, 2000), 46th Annual Meeting, Orlando, FL., Not Applicable, 1999
  • Akhter MP, Cullen D, Recker RR (1999) Alendronate treatment on bone biomechanical properties. Othopaedic Research Society meeting (Abstract #762, 2000), 46th Annual Meeting, Orlando, FL., Not Applicable, 1999
  • B. J. Smith, J. King, E. A. Lucas, MP Akhter, B.H. Arjmandi, B. J. Stoecker (1999) Alteration in vertebral bone quality related to skeletal unloading and copper depletion in mature rats. Experimental Biology 2000., Not Applicable, 1999
  • Akhter MP, Covey M, Cullen DM, Recker RR. Tibial bone response to mechanical loading in two mice breeds. (Poster # SU470) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO., Not Applicable, 1999
  • Akhter MP, Covey M, Cullen DM, Recker RR. Bone mass and strength properties in EP1 knockout and wild type mice. (Poster # SU473) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, Not Applicable, 1999
  • Cullen DM, Peyton AC, Petersen DK, Akhter MP. Aged Rat Bone Response to In Vivo Mechanical Stimulation (Poster # SA414) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO., Not Applicable, 1999
  • Iwaniec UT, Fung YK, Akhter MP, Haven MC, Schmid M, Cullen DM. Effects of nicotine on bone and calcitropic hormones in growing female rats. (Poster # SU350) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, Not Applicable, 1999
  • Cullen DM, Peyton AC, Akhter MP. Aged rat bone response to in vivo mechanical stimulation. (Poster # SA473) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, Not Applicable, 1999
  • Yee JA, Yan L, Cullen DM, Akhter MP, Recker RR. Nicotine inhibits osteoblast differentiation in cultures of neonatal rat calvarial cells. (Poster # F139) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO., Not Applicable, 1999

Presentations

  • V. Peterson, B. Hugenroth, B. Rosauer, D. Cullen, M. Akhter. Osteocyte Lacunar Characteristics as a Function of Genotype and Age in Bone Tissue. (Plenary Session Poster Presentation/abstract #FR0042, ASBMR, October 9-12, 2015, Seattle, WA)., 2015
  • Severine V, Anastasia D, Turner JA, Recker RR, Akhter MP. Intrinsic Material Property Differences in Bone Tissue from Fracturing vs Non-fracturing Women. (Poster Presentation/abstract #SU0042, ASBMR, October 9-12, 2015 Seattle, WA., 2015
  • Brad Hugenroth, Laura Armas, Akhter MP. Bone Structure and Osteocyte Lacunar Properties in Kidney Patients. (Poster Presentation/abstract #MO0258, ASBMR, October 9-12, 2015, Seattle, WA., 2015
  • Seminar (Dr. Akhter MP) July 31, 2015. Variations in shape and size for osteocyte lacunar voids Objectives. Osteoporosis Research Center (ORC)., 2015
  • Seminar (Dr. Akhter MP) April 10, 2015. High resolution scanning of bone tissue and other materials-an overview Research. Osteoporosis Research Center (ORC)., 2015
  • M.P. Akhter, L. Kesavalu, D.E. Kipp, D.B. Kimmel, T.J. Wronski. Comparative analysis of the development of periodontal disease in Rice rats and Lewis rats. J.I. aguirre, S. La, J.G. Messer, J. Yarrow, The Bone Morphometry Meeting, Tokyo Japan, April 2015, 2015
  • Quantifying fatigue loaded microdamage in cortical bone tissue. McDonald D., Hugenroth B., Rosauer B., Akhter MP. Creighton University School of Medicine. 46th Midwest Student Biomedical Research Forum (MSBRF). Oral Presentation. Saturday, February 28, 2015, 2015
  • V. Peterson, B. Hugenroth, B. Rosauer, D. Cullen, M. Akhter. Osteocyte lacunar characteristics as a function of genotype and age in bone tissue. Poster Presentation. Saturday, February 28, 2015, 2015., 2015
  • Seminar (Dr. Akhter MP) January 23, 2015. Osteocyte lacunar characteristics in pre-and postmenopausal biopsies. Osteoporosis Research Center (ORC)., 2015
  • Seminar (Dr. Akhter MP) December 17, 2014. Bone Quality - Nano indentation data. Osteoporosis Research Center (ORC)., 2014
  • Seminar (Dr. Akhter MP) November 21, 2014. Assessment of fatigue damage in bone tissue using microXCT-200 system. Osteoporosis Research Center (ORC)., 2014
  • Akhter MP, Cullen DM, Danforth JD, Alvarez G, Hackfort B, Recker RR. Biomechanical Analyses of Bone Tissue Damage from Fatigue Loading in Vivo. (Poster Presentation/abstract #MO0045, ASBMR 2014, Houston, TX) September 15, 2014, 2014
  • Rosauer BA, Akhter MP, Kimmel BD, Lappe JM, Recker RR. Osteocyte Lacunar Density is Breed Related in Mice. (Plenary Session Poster Presentation/abstract #FR0275, ASBMR 2014, Houston, TX) September 13, 2014., 2014
  • McCumber T, Hackfort B, Akhter MP, Cullen DM. In vivo fatigue damage in bone linked to cytokine expression. (Poster Presentation/abstract #SU0155, ASBMR 2014 Houston, TX), 2014
  • Hackfort B, Akhter MP, Cullen DM. Cyclooxygenase Response to Multiple Mechanical Loads. (Presentation/abstract #MO0046, ASBMR 2014, Houston, TX), 2014
  • Seminar (Dr. Akhter MP) August 7, 2014. High Resolution 3D Imaging from MicroXCT-200 System. Department of Oral and Craniofacial Sciences. UMKC School of Dentistry, Kansas City, MO, 2014
  • Seminar (De. Akhter MP) July 18, 2014. 3D Imaging of Osteocyte Lacunae/Voids in Bone Tissue. Creighton University, Omaha, NE., 2014
  • Cullen, Diane; Akhter, Mohammed; Danforth, John; Alvarez, Gwen; Hackfort, Bryan; Recker, Robert; Inflammatory Signals Associated with In Vivo Fatigue Damage. [ORS, March 15-19, 2014, Poster Session #: PS1-024; Poster#: 0576], New Orleans, LA, 2014
  • Seminar (Dr. Akhter MP) February 21, 2014. MicroXCT-200 System. Creighton University, Omaha, NE., 2014
  • Seminar (Dr. Akhter MP) October 25, 2013 High Resolution MicroXCT-200 Uses in Bone Research. Creighton University, Omaha, NE, 2013
  • Akhter Mp, Danforth J, Kimmel DB, McElwee J, Furia M, Pennypacker BL, Duong LT, Recker RR, Opiteck GJ. Bone Structure and Strength in Three Mouse Crosses as a Function of Strain. (Presentation/abstract Number: SA0041, ASBMR 2013, Baltimore, MD) October 4-7, 2013., 2013
  • Mechanical strain distribution in the ulnae of LRP5 mutant mice. Akhter MP, Lund AD, Glass NE. ORS 2005, poster # 648., 2005
  • LRP5 Gene Influences on Structure and Strength in Femoral Trabecular and Cortical Bone. SA Dubrow, AD Lund, MP Akhter. Midwest Student Biomedical Research Forum (2005), 2005
  • BIOMECHANICAL AND STRUCTURAL PROPERTIES OF LRP5 MUTANT VERTEBRAE. HRUBY PM, AKHTER MP. Midwest Student Biomedical Research Forum (2005), 2005
  • Fox SD, Johnson ML, Cullen DM, Haynatzki G, Akhter MP Differences in loading-related mRNA responses in three mice bredds . The 35th Midwest Student Biomedical Research Forum (MSBRF, abstract #P-27, 2004), Omaha., 2004
  • Kuruvilla SJ, Cullen DM, Haynatzski G, Akhter MP Breed and site specific bone adaptation response to mechanical force. The 35th Midwest Student Biomedical Research Forum (MSBRF, abstract #P-41, 2004), Omaha., 2004
  • Akhter MP, Short S, Wells DJ, Cullen DM Bone adaptation response to mechanical loading in mice ulnae. Poster #M157, 2003, ASBMR 25th Annual Meeting, Minneapolis, MN., 2003
  • D. Y. Soung, D. A. Khalil, L. Devareddy, L. J. Hammond, E. A. Lucas, B. J. Smith, D. D. Marlow, M. P. Akhter, B. H. Arjmandi. Effects of Soy Isoflavones on Bone Biomechanical and Micro-architectural Properties in an Aged Orchidectomized Rat Model of Male Osteoporosis. Poster #SU366, 2003, ASBMR 25th Annual Meeting, Minneapolis, MN., 2003
  • D. M. Cullen, J. Carter, S. Morgan, M. Gentry-Nielsen, M. P. Akhter. Cortical Bone Response to Long-term Smoke and Ethanol Exposure. Poster #SU260, 2003, ASBMR 25th Annual Meeting, Minneapolis., 2003
  • Akhter MP, Wells DJ, Gairola CG (2003) Tobacco Smoke Exposure and Bone Strength in Mice (abstract #1424) Environmental/Ecotoxicology, Inhalants, Particles & Gases, Respiratory Tract., 2003
  • Akhter MP, Wells DJ, Lydia P, Cullen DM (2002) Bone Biomechanical Properties in Prostaglandin EP4 Knock-out Mice. Abstract accepted for 49th Annual meeting of Orthopaedic Research Society (ORS), New Orleans, LA. Poster # 416., 2003
  • Akhter MP, Wells DJ, Lydia P, Cullen DM (2003) Bone Biomechanical Properties in Prostaglandin EP4 Knock-out Mice. Abstract accepted for 49th Annual meeting of Orthopaedic Research Society (ORS), New Orleans, LA. Poster # 416., 2003
  • Biomedical Engineering Seminar, October 2002, Biological systems engineering, Univ. of Nebraska-Lincoln, 2002
  • Akhter MP, Cullen DM, Wells DJ, Johnson ML, Babij P, Haynatzki GR, Recker RR Effects of a mutation in the Lrp5 gene on bone biomechanical properties Poster # M163, 2002, ASBMR 24th Annual Meeting, San Antonio, TX., 2002
  • Akhter MP, Wells DJ, Cullen DM Indomethacin suppresses the bone adaptation response to mechanical loading in C57BL/6J mice Poster # M164, 2002, ASBMR 24th Annual Meeting, San Antonio, TX., 2002
  • DM Cullen, MP Akhter, D Mace, ML Johnson, P Babij, RR Recker, Bone Sensitivity To Mechanical Loads with the Lrp5 HBM Mutation. Poster # M, 2002, ASBMR 24th Annual Meeting, San Antonio, TX., 2002
  • 6) D.A. Khalil, M.P. Akhter , S. Juma, E.A. Lucas, D.S. Galloway, L.J. Hammond, D. Soung, B. J. Smith, R. Recker, B.H. Arjmandi The combination of vitamin E and soy protein exerts added skeletal benefits in an aged rat model of male osteoporosis. Poster # M, 2002, ASBMR 24th Annual Meeting, San Antonio, TX., 2002
  • M.P. Akhter, D.A. Khalil, E.A. Lucas, D.S. Galloway, L.J. Hammond, B. J. Smith, R. Recker, B.H. Arjmandi Soy Isoflavones May Enhance Bone Formation In An Aged Rat Model Of Male Osteoporosis. Poster # M, 2002, ASBMR 24th Annual Meeting, San Antonio, TX., 2002
  • Biomedical Engineering Seminar , July 2002, Minority student research program, 2002
  • MP Akhter M Roy, J Rho, Breed related variation of cortical bone in intrinsic mechanical sproperties. ORS 2002, abstract #566, Dallas Texas (Feb 9-12, 2002)., 2002
  • D Cullen; S Tanner; G Gong; R Smith; M Akhter, Prostaglandin and DNA synthesis in bone with mechanical loading. ORS 2002, abstract #580, Dallas Texas (Feb 9-12, 2002)., 2002
  • AB Arquitt, BH Arjmandi, MP Akhter, Iron deficiency results in lower bone density and lower tibial cortical thicknes in growing female rats. Poster: M037, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • S. Juma, MP Akhter, D Chakkalakal, JR Novak, DA Khalil, EA Lucas, M El-Osta, BJ Stoecker, ED Fritz, BH Arjmandi. Trauma due to fracture reduces biomechanical properties of non-fractured bone in the aged rat model. Poster: SA 345, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • D Chakkalakal, JR Novak, ED Fritz, MP Akhter, EA Lucas, DA Khalil, S Juma, M EL-Osta, BJ Stoecker, BH Arjmandi. Poster: M428, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • DM Cullen, AC Peyton, MJ Gentry-Nielsen, MP Akhter Bone turnover with in vivo smoke and ethanol exposure. Poster: SU 321, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • MP Akhter TW Hull, MJ Gentry-Nielsen, DM Cullen, RR Recker Bone strength properties with tobacco smoke and ethanol exposure in rats. Poster: SU 323, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • MP Akhter, GR Haynatzki, TW Hull, DM Cullen, RR Recker, GC Gairola, Tobacco smoke exposure and bone biomechanical properties. Poster: SU 327, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • 6) BH Arjmandi, MP Akhter, D Chakkalakal, DA Khalil, EA Lucas, S Juma, M El-Osta, L Devareddy, BJ Stoecker, Effects of Isoflavones, Vitamine E, and their combination on bone in an aged rat model of osteopenia. Poster: M427, 2001, ASBMR 23rd Annual Meeting, Phoenix, AZ., 2001
  • Fung YK, Haven MC, Iwaniec UT, Akhter MP, Haynatzki GR, Cullen DM (2001) Effects of nicotine on bone in adult female rats. Society for Research on Nicotine & Tobacco. PO2 26., 2001
  • M. P. Akhter, U. T. Iwaniec, J. K. Otero, M. A. Covey, D. M. Cullen, D. B. Kimmel, R. R. Recker (2000): Genetic Variation in Vertebral Biomechanics and Histomorphometry in Three Breeds of Mice. Poster: SU 713, 2000, ASBMR 22nd Annual Meeting, Toronto., 2000
  • Akhter MP, U. T. Iwaniec, M.A. Covey, Cullen D, Gong G, Recker RR (2000): Nicotine and Biomechanical Properties in Bone. Poster: SU 338, 2000, ASBMR 22nd Annual Meeting, Toronto., 2000
  • U. T. Iwaniec, D. M. Cullen, N. M. Kosta, S. J. Tanner, M. P. Akhter, Y. K. (2000): Fung. Effects of Nicotine on Cancellous Bone in Aged Female Rats. Poster 924, ASBMR 22nd Annual Meeting, Toronto., 2000
  • U. T. Iwaniec, D. M. Cullen, N. M. Kosta, M. P. Akhter, Y. K. Fung (2000): Effects of Nicotine on Cortical Bone in Aged Female Rats Poster: 251 ASBMR 22nd Annual Meeting, Toronto., 2000
  • B. H. Arjmandi, M. P. Akhter, E. A. Lucas, B. J. Stoecker, S. Juma, D. A. Khalil (2000): Prune: Its Influence on Quality of Bone in Ovarian Hormone Deficiency. Poster: 1023 ASBMR 22nd Annual Meeting, Toronto., 2000
  • D. M. Cullen, A. C. Peyton, M. P. Akhter, G. Gong, M. L. Johnson (2000): EP1 Receptor Knockout Mice Response to Mechanical Loading,. Poster: 679 ASBMR 22nd Annual Meeting, Toronto., 2000
  • G. Gong, D. M. Cullen, A. C. Peyton, M. P. Akhter, R. R. Recker (2000): EP1 Antagonist Inhibition of Bone Formation Induced by Mechanical Loading Poster: 684 ASBMR 22nd Annual Meeting, Toronto., 2000
  • D. M. Cullen, A. C. Peyton, M. P. Akhter, G. Gong (2000): Mechanical Loading Response in EP2 Receptor Knockout Mice. Poster 2048 ASBMR 22nd Annual Meeting, Toronto., 2000
  • Akhter MP, Cullen D, Recker RR (2000): Alendronate treatment on bone biomechanical properties. Othopaedic Research Society meeting Poster #762, 2000), 46th Annual Meeting, Orlando, FL, 2000
  • Akhter MP, Cullen D, Gong G, Recker RR (2000): Biomechanical properties of bone in prostaglandin EP2 knockout mice. Othopaedic Research Society meeting Poster # 743, 2000), 46th Annual Meeting, Orlando, FL., 2000
  • Poster: T315. Bone Strength Characteristics In Two Mice Breeds, 1999
  • Akhter MP, Cullen D, Gong G, Recker RR (1999) Biomechanical properties of bone in prostaglandin EP2 knockout mice. Othopaedic Research Society meeting (Abstract # 743, 2000), 46th Annual Meeting, Orlando, FL, 1999
  • Akhter MP, Cullen D, Recker RR (1999) Alendronate treatment on bone biomechanical properties. Othopaedic Research Society meeting (Abstract #762, 2000), 46th Annual Meeting, Orlando, FL., 1999
  • B. J. Smith, J. King, E. A. Lucas, MP Akhter, B.H. Arjmandi, B. J. Stoecker (1999) Alteration in vertebral bone quality related to skeletal unloading and copper depletion in mature rats. Experimental Biology 2000., 1999
  • Breed related bone density and strength characteristics in mice. Midwest Student Biomedical Research Forum (31st Annual Meeting, Omaha, NE). Awarded 2nd Place (BEST ORAL presentation), 1999
  • Akhter MP, Covey M, Cullen DM, Recker RR. Tibial bone response to mechanical loading in two mice breeds. (Poster # SU470) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO., 1999
  • Akhter MP, Covey M, Cullen DM, Recker RR. Bone mass and strength properties in EP1 knockout and wild type mice. (Poster # SU473) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, 1999
  • Cullen DM, Peyton AC, Petersen DK, Akhter MP. Aged Rat Bone Response to In Vivo Mechanical Stimulation (Poster # SA414) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, 1999
  • Iwaniec UT, Fung YK, Akhter MP, Haven MC, Schmid M, Cullen DM. Effects of nicotine on bone and calcitropic hormones in growing female rats. (Poster # SU350) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, 1999
  • Cullen DM, Peyton AC, Akhter MP. Aged rat bone response to in vivo mechanical stimulation. (Poster # SA473) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO., 1999
  • Yee JA, Yan L, Cullen DM, Akhter MP, Recker RR. Nicotine inhibits osteoblast differentiation in cultures of neonatal rat calvarial cells. (Poster # F139) American Society of Bone and Mineral Research, 21ST meeting Sept. 30 - Oct. 4, 1999 in St. Louis, MO, 1999

Awards and Honors

  • Intramural Research Award, 1999
  • Intramural Research Award, 1999
  • Intramural Research Award, 1999