Nancy D. Hanson, PhD
Nancy D. Hanson, PhD

Nancy D. Hanson, PhD

Professor
School of Medicine

Academic Appointments

Department

  • Med. Microbiology & Immunology

Position

  • Professor

Biography

Examples of the most recent publications can be found at this PubMed link.

Education

  • University of Texas - Arlington,1976-1977
  • University of Texas Permian Basin,B.S.,1977-1979
  • University of Nebraska - Omaha,M.A.,1982-1984
  • University of Nebraska Medical Center,Ph.D.,1982-1984

Publications and Presentations

Books

  • Khalaf, Noha G. and Nancy D. Hanson. The scope of bacterial resistance to antibiotics in some countries in the Middle East and North Africa. In A. U. Khan (Ed.), Multidrug Resistance: A Global Concern. Bentham Science Publishers., Not Applicable, 176-205, 2012

Articles

  • Invited article from Medical Lab Management Magazine based on the presentation of the product theater at the May American Society for Microbiology. Title: Rapid multiplex PCR kits for the identification of clinically relevant β-Lactamase genes: Publication date: December 2015, Medical laboratory Management Magazine, 12, 1-3, 2015
  • 6. Geyer, C. N., R. C. Fowler, J. R. Johnson, B. Johnston, S.J. Weissman, P. Hawkey, and N. D. Hanson. 2015. Evaluation of CTX-M steady-state mRNA, mRNA half-life, and protein production in various sequence types of Escherichia coli., J Antimicrob Chemother, doi:10.1093/jac/dkv388, 1-10, 2015
  • 7. Fowler, RC and ND Hanson. 2015. The OpdQ porin of Pseudomonas aeruginosa is regulated by environmental signals associated with cystic fibrosis including nitrate-induced regulation involving the NarXL two-component system. MicrobiologyOpen. 2015 Oct 12. doi: 10.1002/mbo3.305., Not Applicable, doi: 10.1002/mbo3.305. , 2015
  • 8. Ledeboer NA, Lopansri BK, Dhiman N, Cavagnolo R, Carroll KC, Granato P, Thomson R Jr, Butler-Wu SM, Berger H, Samuel L, Pancholi P, Swyers L, Hansen GT, Tran NK, Polage CR, Thomson KS, Hanson ND, Winegar R, Buchan BW. 2015. Identification of Gram-Negative Bacteria and Genetic Resistance Determinants from Positive Blood Culture Broths using the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay. J. Clin MicroJ Clin Microbiol. 2015 Aug;53(8):2460-72. doi: 10.1128/JCM.00581-15, J Clinical Microbiology, 53, 2460-2472, 2015
  • Identification of Gram-Negative Bacteria and Genetic Resistance Ledeboer NA, Lopansri BK, Dhiman N, Cavagnolo R, Carroll KC, Granato P, Thomson R Jr, Butler-Wu SM, Berger H, Samuel L, Pancholi P, Swyers L, Hansen GT, Tran NK, Polage CR, Thomson KS, Hanson ND, Winegar R, Buchan BW.Determinants from Positive Blood Culture Broths using the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay., Journal of Clinical Microbiology, 2015
  • Fowler, R. C, C. R. Scharn, Mir A. Ali, S. J. Cavalieri, R. V. Goering, N. D. Hanson. 2014. Whole genome mapping of the first reported case of KPC-2–positive, Diagnosis Microbiol Infectious Diseases, 79, 384-386, 2014
  • Geyer, C.N. and N.D. Hanson. Multiplex high-resolution melting analysis as a diagnostic tool for the detection of plasmid-mediated AmpC β-lactamase genes., J Clinical Microbiology, 52, 1262-1265, 2014
  • Fowler R. C and N.D. Hanson. Emergence of carbapenem resistance due to the novel insertion sequence ISPa8 in Pseudomonas aeruginosa. PLoS One., PLoS One, 9, e91299, 2014
  • Roth, A. L., P.D. Lister, and N.D. Hanson. Effect of drug treatment options on the mobility and expression of blaKPC., J Antimicrob Chemother, 51, 61-65, 2013
  • Geyer, C.N. and N.D. Hanson. 2013. Rapid PCR Amplification Protocols Decrease the Turn-Around Time for Detection of Antibiotic Resistance Genes in Gram-negative Pathogens. Diagnostic Micro and Infect. Dis., Diagnostic Microbiology and Infectious Disease, 13, 113-117, 2013
  • Roth, A. L. and N. D. Hanson. Rapid Detection and Statistical Differentiation of KPC Gene Variants in Gram-negative Pathogens Using High Resolution Melting and ScreenClust Analysis., J Clinical Microbiology, 51, 61-65, 2013
  • Hu G, Gong AY, Roth AL, Huang BQ, Ward HD, Zhu G, Larusso NF, Hanson ND, Chen XM. 2013. Release of luminal exosomes contributes to TLR4_mediated epithelial antimicrobial defense. 9(4):e1003261. doi: 10.1371/journal.ppat.1003261, PLoS Pathogens, 9, 3261, 2013
  • Hanson, ND Guest Editor. Editorial: Resistance in Gram-negative Pathogens: A Threat to Global Health. Current Pharmaceutical Design, Current Pharmaceutical Design, 19, 163, 2013
  • Roth, A. L., K. S. Thomson, P.D. Lister, and N. D. Hanson. Production of KPC-2 alone does not always result in resistant β-lactam MICs in Gram-negative pathogens., J Clinical Microbiology, 50, 4183-4184, 2012
  • Geyer, C.N., M.D. Reisbig, and N. D. Hanson. 2012. Development of a TaqMan® Multiplex PCR Assay for Detection of Plasmid-Mediated AmpC β-lactamase Genes., J Clinical Microbiology, 50, 3755-3725, 2012
  • Hanson, N. D., A. Hossain, L. Buck, E. S. Moland, and K.S. Thomson. The First Occurrence of a Pseudomonas aeruginosa in the United States Producing an IMP Metallo-â-lactamase, IMP-18., Antimicrob Agents Chemother, 50 (6), 2272-2273, 2006
  • Schmidtke, A. J. and N. D. Hanson. A Model System to Evaluate the Effect of ampD Mutations on AmpC-mediated â-lactam Resistance., Antimicrob Agents Chemother, 50 (6), 2030-2037, 2006
  • Sidjabat H. E., K. M. Townsend, N. D. Hanson, J. M. Bell, H. W. Stokes, K. S. Gobius, S. M. Moss, and D. J. Trott. 2006. Identification of blaCMY-7 and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia, J Antimicrob Chemother, 57 (5), 840-848, 2006
  • AmpC and OprD are not involved in the mechanism of Imipenem hypersusceptibility among Pseudominas aeruginosa isolates overexpressing the mexCD-oprJ efflux pump, Antimicrob Agents Chemother, 49 (11), 4763-4766, 2005
  • Hong, T. E.S. Moland, B. Abdalhamid, N.D. Hanson, J. Wang, C. Sloan, D.Fabian, A. Farajallah, J.Levine, and K.S. Thomosn. Escherichia coli: development of carbapenem resistance during therapy., J Clinical Microbiology, 43 (9), 4891-4894, 2005
  • Hong, T. E.S. Moland, B. Abdalhamid, N.D. Hanson, J. Wang, C. Sloan, D.Fabian, A. Farajallah, J.Levine, and K.S. Thomosn. 2005. Escherichia coli: development of carbapenem resistance during therapy.Clin Infect Dis. 2005 15;40(10):e84-6., Clinical Infectious Diseases, 15, e84-e86, 2005
  • Mortensen, J.E., M. Bemier, L.D. Gray, S. Dolan, N.D. Hanson, E.S. Moland, B. Abdalhamid. 2005. New quality control strain for use in routine testing for production of extended-spectrum Beta-lactamases by enterobacteriaceae. J Clin Microbiol. 43 (5):2545., J Clinical Microbiology, 43, 2545, 2005
  • Pitout, J. D.D., A. Hossain, and N.D. Hanson. 2004. Phenotypic and molecular detection of CTX-M-â-lactamases produced by Escherichia coli and Klebsiella spp. Journal of Clinical Microbiology. 42:5715-5721., J Clinical Microbiology, 42, 5715-5721, 2004
  • Abdalhamid, B., J. D. D. Pitout, and N. D. Hanson. 2004. Community Onset Disease Caused by Citrobacter freundii Producing A Novel CTX-M ƒÒ-lactamase, CTX-M-30, in Canada. Antimicrobial Agents and Chemotherapy. Antimicrobial Agents and Chemotherapy. 48:4435-4437., Antimicrob Agents Chemother, 48, 4435-4437, 2004
  • Hossain, A, Ferraro,M. J., Pino. R. M.3, Dew, R. B. III, Moland, E.S., Lockhart, T. J., Thomson, K. S. Goering, R. V. and Hanson, N.D. 2004. Plasmid-mediated carbapenem hydrolyzing enzyme, KPC-2, in an Enterobacter sp. Antimicrobial Agents and Chemotherapy 48:4438-4440., Antimicrob Agents Chemother, 48, 4438-4440, 2004
  • Reisbig, M.D. and N. D. Hanson. 2004. Promoter sequences necessary for high level expression of the plasmid-associated ampC â-lactamase gene, blaMIR-1. Antimicrobial Agents and Chemotherapy. 48:4177-4182., Antimicrob Agents Chemother, 48, 4177-4182, 2004
  • Liebana, E., M. Batchelor, C. Torres, L. Brinas, L.A. Lagos, B. Abdalhamid, N. D. Hanson, J. Martinez-Urtaza. 2004. Pediatric Infection due to multi-resistant Salmonella enterica Serotype Infantis in Honduras. Journal of Clinical Microbiology. 42:4885-4888., J Clinical Microbiology, 42, 4885-4888, 2004
  • Wolter D. J., E. Smith-Moland, R. V. Goering, N. D. Hanson, and P.D. Lister. 2004. Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital. Diagn Microbiol Infect Dis. 2004 50:43-50., Diagnostic Microbiology and Infectious Disease, 50, 43-50, 2004
  • Wolter, D., N.D. Hanson, P.D. Lister. 2004. Insertional inactivation of oprD in clinical isolates of Pseudomonas aeruginosa leading to carbapenem resistance. FEMS Microbiology Letters. 236:137-143., FEMS MIcrobiology Letters, 236, 137-143, 2004
  • Pitout, J.D.D., N.D. Hanson, D. L. Church, and K. B. Laupland. 2004. Population-based laboratory Surveillance for Escherichia coli-producing extended-spectrum â-lactamases: importance of community isolates with blaCTX-M genes., Clinical Infectious Diseases, 38, 1736-1741, 2004
  • Hossain, A., M.D. Reisbig, and N.D. Hanson. 2004. Plasmid-encoded factors compensate for the biological cost of AmpC over-expression in a clinical isolate of Salmonella typhimurium., Journal of Antimicrobial Chemotherapy, 53, 964-970, 2004
  • Liebana, E., M. Gibbs, C. Clouting, L. Barker, F. Glifton-Hadley, E. Pleydell, B. Abdalhamid, N. D. Hanson, L. Martin, C. Poppe, R. Davies. 2004. Characterization of Beta-lactamases Responsible for Resistance to Extended-Spectrum Cephalosporins in Escherichia coli and Salmonella enterica Strains from Food-Producing Animals in United Kingdom., Microbial Drug Resistance, 10, 1-9, 2004
  • Pitout, J.D., M.D. Reisbig, L. Chui, M. Louie, L. Crowe, D. L. Church, S. Elsayed, D. Gregson, R. Ahmed, G. Soule, P. Tilley, and N. D. Hanson. 2003. Association between the Handling of Pet Treats and Infection with Salmonella enterica serotype Newport expressing the AmpC beta-lactamase, CMY-2., J Clinical Microbiology, 41, 4578-4582, 2003
  • Pitout, J. D. D., M. D. Reisbig, E. C. Vennter, D. L. Church, and N. D. Hanson. 2003. Modification of the double-disk test for the detection of Enterobacteriaceae producing extended-spectrum (ESBLs) and AmpC â-Lactamases, J Clinical Microbiology, 41, 3933-3935, 2003
  • Leading Article Nancy D. Hanson AmpC Beta-Lactamases: what do we need to know for the future?, Journal of Antimicrobial Chemotherapy, 52, 2-4, 2003
  • Moland, E.S, S. Pottumarthy, J. A. Black, A. Hossain, N. D. Hanson, and K. S. Thomson. 2003. Discovery of CTX-M-like ESBLs in E. coli Isolates from Five States in the USA, Antimicrob Agents Chemother, 47, 2382-2383, 2003
  • Reisbig, M.D., A. Hossain, and N.D. Hanson Factors Influencing Gene Expression and Resistance for Gram-Negative Organisms Expressing Plasmid-Encoded ampC genes of Enterobacter Origin., J Antimicrob Chemother, 51, 1141-1151, 2003
  • Mahlen, S. D., S. Morrow,Baha Abdalhamid, and N.D. Hanson. Analyses of ampC gene expression in Serratia marcescens reveal new regulatory properties., Journal of Antimicrobial Chemotherapy, 51, 791-802, 2003
  • Moland, E.S., N. D. Hanson, V. L. Herrera, J. A. Black, T. J. Lockhart, A. Hossain, J.A. Johnson, R. V. Goering, and K. S. Thomson. Plasmid-mediated, carbapenem-hydrolysing â-lactamase, KPC-2, in Klebsiella pneumoniae isolates., J Antimicrob Chemother, 51, 711-714, 2003
  • Coudron, P.E., N. D. Hanson, and M. W. and Climo. 2003. Occurrence of Extended-Spectrum and AmpC Beta-Lactamases in Bloodstream Isolates of Beta-Klebsiella pneumoniae: Isolates Harbor Plasmid-mediated FOX-5 and ACT-1 AmpC â-Lactamases., Journal of Clinical Microbiology, 41, 772-777, 2003
  • Moland, E.S, J. A. Black, J. Ourada, M. D. Reisbig, N. D. Hanson, and K. S. Thomson. Occurrence of Newer ƒÒ-lactamases in Klebsiella pneumoniae Isolates from 23 United States Hospitals., Antimicrob Agents Chemother, 46, 3837-3842, 2002
  • Hanson,N.D., E.S. Moland, A. Hossian, S.A. Neville, I.B. Gosbell, and K.S. Thomson. 2002. Unusual Salmonella enterica serotype Typhimurium isolate producing CMY-7, SHV-9, and OXA-30 Beta-lactamases., Journal of Antimicrobial Chemotherapy, 49, 1011-1014, 2002
  • Perez-Perez, F. J. and N.D.Hanson. 2002. Detection of Plasmid-Mediated AmpC Beta-Lactamase Genes in Clinical Isolates by Using Multiplex PCR., Journal of Clinical Microbiology, 40, 2153-2162, 2002
  • Riesbig, M.D. and N. D. Hanson. The ACT-1 Plasmid-Mediated AmpC Beta-lactamase is Inducible: Detection in a complicated Beta-lactamase Background., Journal of Antimicrobial Chemotherapy, 49, 557-560, 2002
  • Hanson, N.D., Moland, E.S., and Pitout, J.D.D. 2001. Enzymatic characterization of TEM-63, a TEM-type extended spectrum -lactamase expressed in three different genera of Enterobacteriaceae from South Africa., Diagnostic Microbiology and Infectious Disease, 40, 199-201, 2001
  • Molecular characterization of a multiply resistant Klebsiella pneumoniae eoncoding ESBLs and a plasmid-mediated AmpC. J. Antimicrobial Chemotherapy 44:377-380, Not Applicable, 1999
  • Regulation of Inducible AmpC Beta_lactamase Expression Among Enterobacteriaceae, Current Pharmaceutical Design, 1999 5:881-894, Not Applicable, 1999
  • Moland, E. S., J. Johnson, J.A. Black, T.J. Lockhart, A. Hossain, V.L. Herrera, R.V.Goering, N.D. Hanson, and K. S. Thomson. 2002. Klebsiella pneumoniae (KP) Isolates Producing a Carbapenem Hydrolyzing Enzyme (CHE). Submitted to Journal of Antimicrobial Chemotherapy
  • Mahlen, S. D., S. Morrow, Baha Abdalhamid and N.D. Hanson. 2002. Analyses of the ampC Gene Expression in Serratia marcescens Reveal New Regulatory Properties. Submitted to Journal Antimicrobial Chemotherapy
  • Reisbig, M.D., A. Hossain, and N.D. Hanson**. 2002. Factors Influencing Gene Expression and Resistance for Gram-Negative Organisms Expressing Plasmid-Encoded ampC genes of Enterobacter Origin. Submitted to Journal of Antimicrobial Chemotherapy
  • Wolter, D.J., N.D. Hanson, and P.D. Lister. 2002. Transcriptional Expression of MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY Efflux Pumps in Wild-type P. aeruginosa. Submitted to Journal of Antimicrobial Chemotherapy
  • Moland, E.S, J. A. Black, J. Ourada, M. D. Reisbig, N. D. Hanson, and K. S. Thomson. 2002. Occurrence of Newer Beta-lactamases in Klebsiella pneumoniae Isolates from 23 United States Hospitals. Antimicrobial Agents and Chemotherapy. In press.
  • Coudron, P.E., N. D. Hanson, and M. W. and Climo. 2002. Occurrence of Extended-Spectrum and AmpC Beta-Lactamases in Bloodstream Isolates of Beta-Klebsiella pneumoniae: Isolates Harbor Plasmid-mediated FOX-5 and ACT-1 AmpC Lactamases. Accepted to Journal Clinical Microbiology

Publications

  • Symposium Talk, Invited Speaker. Mobile Genetic Elements Associated with Beta-Lactam Resistance, Regional American Society of Microbiology Abstracts, 2006
  • Amber Schmidtke and Nancy D Hanson. Molecular Characterization of the ampD Promoter of Pseudomonas aeruginosa, Regional American Society of Microbiology Abstracts, 2006
  • Phenotypic Reversion of Imipenem Hypersusceptibility among mexCD-oprJ-Oeverexpressing P. aeruginosa: a complex system becomes more complex. 2005. D. J. Wolter, N. D. Hanson, P.D. Lister. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • Apparent Acquistion of ESBL Leading to Treatment Failure during Cefepime (FEP) Therapy of Klebsiella pneumoniae (KP) Bacteremia. W. Song, E. Smith Moland, N. D. Hanson, J. S. Lewis, J. H. Jorgensen, and K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C, 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • A Novel Mechanism of AmpD-Mediated Derepression in an Isolate of Citrobacter freundii. A. J. Schmidtke and N.D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • Correlation of ampC Induction with PBP Binding in Enterobacter cloacae. B. Abdalhamid, P. A. Wickman, and N. D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • Efflux Pump and Porin Alterations in a Supersuceptible (SS) Strain of P. aeruginosa (PA). D. J. Wolter, J. A. Black, P. D. Lister, N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • OXA-30-Like â-lactamases in E. coli Hydrolyze Cefepime. E. S. Moland, N. D. Hanson, C. Shubert, K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • In Vitro Development of Resistance to DX-619 (DX) and Other Quinolones (Qs) in Enterococcus faecium. P. Wickman, J. A. Black, E. Smith Moland, K. S. Thomson, and N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2005
  • Occurrence of Proteus mirabilis producing FOX-5 plasmid-mediated AmpC beta-lactamase in USA. Black, J.A., E.S. Moland, A. Hossain, G.A. Denys, , T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Klebsiella isolates that Co-produce ESBL and inducible DHA-like plasmid-mediated AmpC beta-lactamases from Baltimore, MD and Tampa, FL. Black, J.A., E.S. Moland, A. Hossain, J.A. Johnson, M. Campbell, T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Development of a Model System to Determine the Effect of ampD mutations on â-lactam Resistance. 2004. A. J. Schmidtke and N.D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • The First Occurrence of a Pseudomonas aeruginosa in the United States (US) Producing and IMP Metallo-â-lactamase (MBL). N.D.Hanson, A. Hossain, L. Buck, E.S. Moland, and K.S. Thomson. 2004 In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Beta-lactam MICs and differential expression of blaCMY-2 reflect dual promoter activity. M.D. Reisbig and N.D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Comparison of ampC transcript half-life among three genera of Enterobacteriaceae. B. Abdalhalmid and N. D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • A community-wide outbreak of clonally related Escherichia coli producing CTX-M-type â-lactamases in the Calgary Health Region (CHR).2004. J. D. D. Pitout, D. B. Gregson, D. L. Church, K. B. Laupland, S. Elsayed, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Increased Expression of ampC in Pseudomonas aeruginosa mutants following exposure to ciprofloxacin (CIP). D. J. Wolter, N.D. Hanson, and P.D.Lister. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, 2004
  • Survey of cefoxitin (FOX) non-wusceptible (NS) E. coli urine isolates (UIs) reveals a high incidence of plasmid-encoded AmpC (pAmpC) â-Lactamase (âL) Producers. 2004. M.D. Reisbig, S.J. Cavalieri, H.A. Hashish, R.V. Goering, and N.D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA, American Society for Microbiology, 2004
  • Paediatric infection due to multi-resistant Salmonella Infantis carrying blaCMY-2, blaTEM-1, blaCTX-M-15 and blaSHV-5 â-lactamases. 2004. E. Liebana, J. Martinez-Urtaza, M. Batchelor, C. Torres, L. Brinas, L.A. Lagos, B. Abdalhamid, N.D. Nanson, F.A. Clifton-Hadley, R.H. Davies. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA., American Society for Microbiology, 2004
  • Evaluation of cefepime (FEP) with and without clavulanic acid (CA) for the detection of ESBLs (Extended Spectrum Beta-Lactamases) in Enterobacteriaceae species. 2004. E. Smith Moland, T.J. Lockkhart, J.A. Black, L.B. Olson, A. HOssain, N.D. Hanson, and K.S. Thomson. In Clinical Microbiology and Infection. 14th European Congress of Clinical Microbiology and Infectious Diseases., European Congress on Clinical Microbiology and Infectious Diseases, 2004
  • Laboratory Diagnosis of Escherichia coli and Klebsiella spp. producing CTX-M-ß-lactamases. 2004. J. D. D. Pitout, A. Hossain, D. L. Church, N. D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA., American Society for Microbiology, 2004
  • Abdalhamid, B. and N. D. Hanson. Differential half-life of the ampC transcript between three genera of Enterobacteriaceae. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri., Missouri Valley Branch Regional American Society for Microbiology, 2004
  • Schmidtke, A. and N. D. Hanson. AmpD mutations in E. coli. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri., Missouri Valley Branch Regional American Society for Microbiology, 2004
  • Molecular Analysis of 10 Putative Efflux Genes in Streptococcus pneumoniae (SP) Reveals Widespread Differences Between Wildtype (WT) Strains and Multi-Drug Resistant (MDR) Clinical Isolates. 2003. P.A. Wichman, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Emergence of Fluoroquinolone (FQ) Resistant Pseudomonas aeruginosa (PA) in a Cystic Fibrosis (CF) Patient: Discordance between MexEF-OprN and Carbapenem Susceptibility. 2003. D.J. Wolters, J. Black, D. Acquazzino, R. Goering, P.Sammut, N. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Molecular Analysis of 10 Putative Efflux Genes in Streptococcus pneumoniae (SP) Reveals Widespread Differences Between Wildtype (WT) Strains and Multi-Drug Resistant (MDR) Clinical Isolates. 2003. P.A. Wichman, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Insertional Inactivation of oprD in Clinical Isolates of Pseudomonas aeruginosa Leading to Carbapenem Resistance. 2003. D.J. Wolter, N. Hanson, P. Lister. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Characterisation of beta-lactamases Responsible for Resistance to Extended-Spectrum Cephalosporins in E. coli and S. enterica from U.K. Food Animals. 2003. E. Liebana, M. Gibbs, C. Clouting, L. Barker, F. Clifton-Hadley, E. Pleydell, B. Abdalhamid, N. Hanson, L. Martin, C. Poppe, R. Davies. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • E. coli producing KPC-3 carbapenem hydrolyzing enzyme (CHE). 2003. T. Hong, E.S. Moland, B. Abdalhamid, N.D. Hanson, J. Wang, C. Sloan, D. Fabian, A. Farajallah, J. Levine, K.S. Thomson. 2003. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Prevalence of Plasmid-mediated AmpC beta-lactamases in Klebsiella pneumoniae (KP), Klebsiella oxytoca (KO), Proteus mirabilis (PM), and Salmonella (S) Isolates from 42 ICU and 21 non-ICU Sites in the United States. 2003 J.A. Black, E.Smith Moland, A. Hossain, T.J. Lockhard, L.B. Olson, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Deletional Analysis of the blaMir-1 Upstream Region Reveals a Novel Promoter Necessary for High-Level Expression and ƒÒ-Lactam Resistance. 2003. M. D. Reisbig and N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Citrobacter freundii from Canada Producing A Novel CTX-M Gene, blaCTX-M-30. 2003. A. Abdalhamid, J.D.D. Pitout, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Surveillance for Escherichia coli Producing CTX-M-Type ƒÒ-Lactamases in the Calgary Health Region (CHR). 2003. J.D.D. Pitout, K.B. Laupland, D.L. Church, S. Elsayed, D. Gregson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Detection of CTX-M-Like ESBLs in Thirteen States within the USA. 2003. E.S. Moland, J.A. Black, K.S. Thomson, N.D. Hanson, T. J. Lockhart, L.B. Olson, A. Hossain.In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • First Report of Plasmid-encoded (PE) Carbapenem Hydrolyzing Enzyme (CHE) KPC-2 in Enterobacter cloacae (EC). 2003 A. Hossain, M.J. Ferraro, R.M. Pino, R.B. Dew III, E.S. Moland, T.J. Lochart, K.S. Thomson, R.V. Goering, and N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • A New Quality Control Strain for Routine Testing for Production of Extended Spectrum Beta-Lactamases (ESBL). 2003. J.E. Mortensen, M. Bernier, L. Gray, S. Doland, E.S. Moland, B. Abdalhamid, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Prevalence of ESBLs in the United States. 2003. E. Smith Moland, J.A. Black, N.D. Hanson, A. Hossain, B. Abdalhamid, W. Song, T.J. Lockhart, L.B. Olson, K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Occurrence of a CTX-M-1-like ESBL in a U.S. Isolate of Citrobacter freundii (CF). 2003. S.E. Sharp, C. Suarez, E. Smith Moland, A. Hossain, N.D. Hanson, and K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • A Novel Mechanism of Resistance to Ciprofloxacin (CIP) and Ethidium Bromide (EB) in Streptococcus pneumoniae (SP): Downregulation of a Putative Permease. 2003. P.A. Wichman, G. A. Perry, K.S. Thomson, N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, Interscience Conference on Antimicrobial Agents and Chemotherapy, 2003
  • Daniel J. Wolter, Nancy D. Hanson, and Philip D. Lister. Multi-Drug Resistance Associated with mexXY Expression in Clinical Isolates of Pseudomonas aeruginosa from a Texas Hospital. In Abstracts of the 13th Congress of Clinicacl Microbiology and Infectious Diseases, Glasgow, United Kingdom, Abstract Book, 9, 0294, 2003
  • A. Hossain, Reisbig. M.D., and N.D. Hanson. High-level expression of the plasmid-encoded AmpC gene, blaCMY-7 does not compromise the virulent phenotype of a strain of Salmonella typhimurium. In Abtracts of the 13th European Congress of Clinical Microbiology aand Infectious Disease, Glasgow, United Kingdom, Abstract Book, 2003
  • M.D. Reisbig and N.D. Hanson. Variations in â-Lactam Susceptibilities Between Organisms Expressing the Plasmid-Encoded AmpC beta-lactamase CMY-2 is Attributed to Variable Gene Expression. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, Abstract Book, 2003
  • D WOLTER, M. REISBIG, N. HANSON, P. LISTER. Pharmacodynamics of Cefepime-Aztreonam Combination against Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients. In Abstracts of the 13th European Congresss of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, Abstract Book, 9, 0392, 2003
  • A. Hossain. P. Wickman, K. S. Thomson and N.D. Hanson Molecular analysis of Streptococcus pneumoniae mutants selected by DK-507k, an investigational fluoroquinolone. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, Abstract Book, 9, 2003
  • P.A. Wickman*, A. Hossain, K.S. Thomson, and N.D. Hanson Differences in selection of efflux-mediated fluoroquinolone resistance in penicillin-susceptible and -resistant Streptococcus pneumoniae after repeated exposure to ciprofloxacin and moxifloxacin. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, Abstract Book, 9, P1549, 2003
  • Discovery of CTX-M-like ESBLs in E. coli Isolates from Five States in the USA. 2002. E. Smith Moland, S. Pottumarthy-Boddu, J.A. Black, A. Hossain, N.D. Hanson, K.S. Thomson. In Abstracts Addendum of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., Abstract Book, 2002
  • Hossain, A., E.S. Moland, J.A. Black, N.D. Hanson, K.S. Thomson. 2002. DQ-113: In Vitro development and Mutational Analysis of Resistance in Staphylococcus aureus, Penicillin Resistant Streptococcus pneumoniae (PRSP) and Vancomycin Resistant Enterococci (VRE). In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., Abstract Book, 2002
  • Pitout, J.D., E.Smith-Moland, S. Elsayed, N. Hamilton, J. Conly, D. Church, N. Hanson. 2002. A Novel Carbapenem-Hydrolyzing Enzyme (CHE) Produced by an Enterobacter cloacae Isolate from Canada. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., Abstract Book, 2002
  • Wolter, D. J., N.D. Hanson, and P. D. Lister. 2002. Continued Expression of mexCD-oprJ Among Phenotypic Revertants of Pseudomonas aeruginosa (PA) that Have Lost Their Fluoroquinolone Resistance. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., Abstract Book, 2002
  • Wolter, D. J., T. J. Lockhart, N.D. Hanson, and P.D. Lister. 2002. Imipenem Hypersusceptibility Among mexCD-oprJ Hyperexpressing Mutants of Pseudomonas aeruginosa does not Involve Decreased expression of ampC or Increased Expression of oprD. In Abstracts of the 42nd Interscience, Abstract Book, 2002
  • Reisbig, M.D. and N.D. Hanson. 2002. Therapeutic Implications for the Plasmid-Encoded (PE) AmpC beta-Lactamase, ACT-1, Expressed in ampD- E. coli. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., Abstract Book, 2002
  • Morrow, S.S. and N.D. Hanson. 2002. Differentiation of Multiple SHV or FOX Genes Using Denaturing High Performance Liquid Chromatography. 2002. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., Abstract Book, 8, 2002
  • Reisbig, M.D. and N.D. Hanson. 2002. The Role of Gene Copy Number in Overall Expression of ampC Genes of Enterobacter cloacae Origin. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., Abstract Book, 16, 2002
  • Wolter, D.J., N.D. Hanson, G. Haynatzki, and P.D. Lister. 2002. Efflux-Mediated Resistance Among Pseudomonas aeruginosa: Complex Regulation of a Complex Resistance Mechanism. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., Abstract Book, 25, 2002
  • Wickman, P.A., A. Hossain, K.S. Thomson, and N.D. Hanson. 2002. Moxifloxacin has Reduced Potential to Select Mutational Fluoroquinolone Resistance in Streptococcus pneumoniae. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., Abstract Book, 4, 2002
  • Moland, E.S., K.K. Sandu, M.R. Pincus, J.A. Black, M.D. Reisbig, N.D. Hanson, K.S. Thomson. 2002. A Simple Phenotypic Approach to the Detection of Inducible Plasmid-mediated AmpC -lactamse (pAmpC) Production in Two New York Isolated of Klebsiella pneumoniae (KP). In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., Abstract Book, 83, 2002
  • Hanson, N.D., S.A. Neville, I.B. Gosbell, A. Hossain, E.S. Moland, and K.S. Thomson. 2001. Salmonella enterica serotype Typhimurium producing CMY-7, SHV-9 and OXA-30 beta-Lactamases. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Mahlen, S.D. and N.D. Hanson. 2001. The Stem-Loop Structure in the 5’Untranslated Region (5’UTR) of the ampC Transcript of Serratia marcescens is Involved in Transcript Stability. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation given by N.D. Hanson., Abstract Book, 2001
  • Reisbig, M.D. and N.D. Hanson. 2001. The Plasmid-mediated AmpC -Lactamase, ACT-1, is Inducible in a Multiply Resistant Klebsiella pneumoniae Isolate. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Herrera, V.L. and N.D. Hanson. 2001. Complex Expression of Novel Plasmid-mediated AmpC -Lactamase Gene. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., AACR Proceedings Apoptosis and Cancer, 2001
  • Jiang, Y., E.S. Moland, Y.Ni, N.D. Hanson. 2001. Novel Mutations in the Promoter and Attenuator Regions of Hyperproducing AmpC E. coli strains from China. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Hossain, A., E.S. Moland, J.A. Black, S.A. Chartrand, N.D. Hanson, K.S. Thomson. 2001. A New Fluoroquinolone (FQ) With a Low Frequency of Mutational Resistance in MRSA. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Moland, E.S., J. Johnson, J.A. Black, T.J. Lockhart, A. Hossain, V.L. Herrera, R.V. Goering, N.D. Hanson, and K.S. Thomson. 2001. Klebsiella pneumoniae (KP) Isolates Producing a Carbapenem Hydrolyzing Enzyme (CHE). In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Moland, E.S., T.J. Cleary, M.D. Reisbig, Y. Jiang, P.E. Coudron, T.J. Lockhart, N.D. Hanson, K.S. Thomson. 2001. Occurrence of Inducible Plasmid-mediated AmpC -lactamase (ipAmpC), DHA-1, in a Miami Isolate of Klebsiella pneumoniae: New Implications for Susceptibility Testing? In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Coudron, P.E., S.M. Tallent, E.S. Moland, N.D. Hanson, M.B. Edmond, R.P. Wenzel. 2001. Occurrence of Extended-Spectrum (ESBL) and AmpC Beta-Lactamases (BLs) in U.S. Bacteremic Isolates of Klebsiella pneumoniae (Kp): Two Isolates Harbor Inducible Plasmid-Mediated ACT-1-Like BLs. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., Abstract Book, 2001
  • Identification, Cloning and Sequencing of a Novel FOX Plasmid-Mediaated AmpC, N.D. Hanson, P. Coudron, E.S. Moland and C.C. Sanders 39th ICAAC. San Francisco,, Not Applicable, 1999
  • Sequence Analysis of the ampC and ampR Regions of Serratia marcescens Reveals a Unique 5' Untranslated Region in ampC. S.S. Morrow, C.C. Sanders, and N.D. Hanson 39th ICAAC San Francisco,, Not Applicable, 1999
  • Molecular Characterization of Mutants Responsible for Dichotomous Fluoroquinolone Resistance in Staphlococcus aureus, A.F. Ehrhardt, C.C. Sanders, K.S. Thomson, N.D. Hanson,39th ICAAC, San Francisco;, Not Applicable, 1999
  • Differential induction of the chromosomal beta-lactamse gene of Serratia marcescens by beta-lactam antibiotics, Missouri Valley Branch, Regional ASM, Tulsa, OK;, Not Applicable, 1999
  • Cloning and sequencing of the chromosomally encoded ampC and ampR genes of Serratia marcescens, Transcriptional analysis of Serratia marcescens ampC, Mahlen, S.D. C.C. Sanders, and N.D. Hanson,Southwestern and Rocky Mountain Division American Association for the Advancement of Science, Creighton University, Omaha, NE, Not Applicable, 1999

Presentations

  • ASM Distinguished Lecturer: The Regulation of β-Lactamase Production How many variations can there be?, 2016
  • American Society for Microbiology Distinguished Lecturer Program: Baltimore MD Molecular Diagnostics: Current and Future Applications for Detection of Antibiotic Resistance Mechanisms, 2016
  • November 7, 2015: Invited Symposium Speaker for the Association for Molecular Pathologists. Title of the talk: Molecular Detection of β-Lactamase Genes: Why and How?, 2015
  • October 7, 2015. Invited Lecturer selected by the graduate students at K-State University. Title of the talk: Molecular Detection of β-Lactamase Genes: The Human/Animal Connection, 2015
  • September 26, 2015. Dr. Hanson gave the American Society Distinguished Lecture for the joint meeting for the Kentucky/Tennessee Branch of the American Society of Microbiology. Title of the talk: The Global Explosion of Gram-negative β-lactamase Producers: What can be done?, 2015
  • September 24, 2015. Dr. Hanson gave a seminar to the Biology Department at Middle Tennessee State University. Title of the talk: The Regulation of β-Lactamase Production: How many variations can there be?, 2015
  • Interscience Conference on Antimicrobial Agents and Chemotherapy. title: 7-plex and 10-plex PCR assays for the detection of ampC, blaCTX-M, and 5 carbapenemase genes using rapid PCR amplification., 2015
  • 7-plex and 10-plex PCR assays for the detection of ampCs, blaCTX-Ms, and 5 carbapenemase genes using rapid PCR amplification. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA., 2015
  • KPC translational efficiency differs between sequence type 131 (ST131) and non-ST 131 E. coli. L.B. Harrison, Y. Doi, N.D. Hanson. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA. Poster Presentation., 2015
  • Development of an eighteen-minute multiplex PCR assay for the simultaneous detection of 6 OXA carbapenemases. R.C. Fowler and N. D. Hanson. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA. Poster Presentation., 2015
  • American Society of Microbiology Distinguished Lecturer: Regulation of Beta-lactamase production: How many variations can there be? Northern California ASM Branch Meeting., 2015
  • American Society of Microbiology Distinguished Lecturer: Global Explosion of Gram‐Negative β‐lactamase Producers: What can be done? Northern California ASM Branch Meeting., 2015
  • Gram-Negative Innovation Day: “Learn & Imagine The Global Explosion of Gram‐Negative β‐lactamase Producers: What can be done?” Lexington, MA. Sponsored by Cubist, 2014
  • One 22-minute multiplx assay for the detection of 9 targets including ampCs, ESBLs, MBLs, and KPCs using Rapid PCR Amplification. N.D. Hanson Speaker. In Abstracts of the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington DC. Sponsored by Streck., 2014
  • 1. The Rapid Detection of ampC Resistance Genes in Gram-negative Bacteria. N.D. Hanson Speaker. In Abstracts of the 114th American Society of Microbiology. Boston MA. Sponsored by Streck., 2014
  • Identification of Promoter Sequences required for the Expression of the Porin Gene opdQ of Pseudomonas aeruginosa. Randal Fowler and N. D. Hanson. 2014. In Abstracts of the 114th American Society of Microbiology. Boston MA. Poster Presentation., 2014
  • Overproduction of the Porin OpdQ is Associated but not Responsible for Multidrug Supersusceptibility (SS) in Carbapenem-selected Mutants of Pseudomonas aeruginosa (PA). R. Fowler and N. D. Hanson. 2014. In Abstracts of the 114th American Society of Microbiology. Boston MA. Poster Presentation., 2014
  • One sixteen minute multiplex assay for the detection of AmpCs, ESBLs, MBLs and KPCs using Rapid PCR Amplification. C. Geyer, S. Morrow, and, N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spa, 2014
  • The Discordant Relationship Between CTX-M-15 mRNA and Protein Production does not Interfere With Beta-Lactam/Beta-Lactamase Inhibitor Combination Susceptibilities in Escherichia coli. C.Geyer, R. Fowler, and N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spain., 2014
  • The mRNA half-life of CTX-M-15 transcripts is controlled by a factor encoded on the blaCTX-M-15 containing plasmid. C. Geyer, and N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spain., 2014
  • Gram-negative Summit: Gram-negative Multi-Drug Resistant Mechanisms. June 18, 2013. Boston MA. Sponsored by Cubist., 2013
  • 1. Rapid Detectin of KPC Gene Variants in Gram-negative Pathogens Using High-Resolution Melting and ScreenClust Analyses. N.D. Hanson Speaker. In Abstracts of the 115th American Society of Microbiology. Denver CO. Sponsored by Qiagen., 2013
  • Identification of family-specific plasmid-mediated AmpC β-lactamase (pmAmpC) genes using multiplex PCR and High Resolution Melth (HRM) Analysis. C. N. Geyer and N. D. Hanson. 2013. In Abstracts of the 113th American Society of Microbiology. Denver CO. Poster Presentation., 2013
  • 1. Carbapenem resistance is not associated with virulence of Pseudomonas aeruginosa using the Dictyostelium discoideum virulence model. R. Fowler, A.T. Weber, and N. D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA Poster Presentation., 2012
  • High resolution melting analysis allows rapid detection and differentiation of blaKPC alleles in Gram-ngative pathogens. A. L. Roth, M. Kovarik, and N.D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation., 2012
  • Evaluation of blaCTXM14 and blaCTXM15 Identifies Differential Gene Expression Among Sequence Type 131 and Non-ST131 E. coli. C. N. Geyer, S. Weissman, P. Hawkey and N. D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation., 2012
  • Kinetic Characterization of a novel VIM (VIM-28) Metallo--lactamase in Pseudomonas aeruginosa isolates from Egypt. A. Yoshizumi, Y. Ishii, T.S.El-Mahdy, N. D. Hanson, and K. Tateda. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation., 2012
  • HudsonAlpha Institute. Huntsville, Alabama. Institutional Seminar Speaker. August 9, 2012. Title: “The Impact of Molecular Testing to Control the Antibiotic Resistance Crisis Caused by Gram-Negative Pathogens”, 2012
  • Symposium Talk for the Regional American Society of Microbiology Meetngs in Kansas City. "Mobile Genetic Elements Associated with Beta-Lactam Resistance, 2006
  • Amber Schmidtke and Nancy D Hanson. Molecular Characterization of the ampD promoter of Pseudomonas aeruginosa. Oral presentation, 2006
  • Efflux Pump and Porin Alterations in a Supersuceptible (SS) Strain of P. aeruginosa (PA). D. J. Wolter, J. A. Black, P. D. Lister, N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster presentation, 2005
  • Phenotypic Reversion of Imipenem Hypersusceptibility among mexCD-oprJ-Oeverexpressing P. aeruginosa: a complex system becomes more complex. 2005. D. J. Wolter, N. D. Hanson, P.D. Lister. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Oral Presentation, 2005
  • In Vitro Development of Resistance to DX-619 (DX) and Other Quinolones (Qs) in Enterococcus faecium. P. Wickman, J. A. Black, E. Smith Moland, K. S. Thomson, and N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster Presentation, 2005
  • A Novel Mechanism of AmpD-Mediated Derepression in an Isolate of Citrobacter freundii. A. J. Schmidtke and N.D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Oral presentation, 2005
  • Correlation of ampC Induction with PBP Binding in Enterobacter cloacae. B. Abdalhamid, P. A. Wickman, and N. D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. oral presentation, 2005
  • Apparent Acquistion of ESBL Leading to Treatment Failure during Cefepime (FEP) Therapy of Klebsiella pneumoniae (KP) Bacteremia. W. Song, E. Smith Moland, N. D. Hanson, J. S. Lewis, J. H. Jorgensen, and K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C Poster Presentation, 2005
  • Invited Symposium Speaker: American Society of Microbiology 45th Interscience Conference on Antimicrobial Agents and Chemotherapy: Washington DC, USA: December 2005. “Detection of Extended Spectrum â-lactamases and Plasmid-mediated AmpC â-lactamases Using Phenotypic and Molecular Tests., 2005
  • OXA-30-Like â-lactamases in E. coli Hydrolyze Cefepime. E. S. Moland, N. D. Hanson, C. Shubert, K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster presentation, 2005
  • Society for General Microbiology, Edinburgh, Scotland. Symposium Lecture April 2004. Title: Molecular Mechanisms of AmpC Gene Expression and the Clinical Implications Associated with Gram-negative Pathogens., 2005
  • A community-wide outbreak of clonally related Escherichia coli producing CTX-M-type â-lactamases in the Calgary Health Region (CHR).2004. J. D. D. Pitout, D. B. Gregson, D. L. Church, K. B. Laupland, S. Elsayed, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Klebsiella isolates that Co-produce ESBL and inducible DHA-like plasmid-mediated AmpC beta-lactamases from Baltimore, MD and Tampa, FL. Black, J.A., E.S. Moland, A. Hossain, J.A. Johnson, M. Campbell, T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Occurrence of Proteus mirabilis producing FOX-5 plasmid-mediated AmpC beta-lactamase in USA. Black, J.A., E.S. Moland, A. Hossain, G.A. Denys, , T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Increased Expression of ampC in Pseudomonas aeruginosa mutants following exposure to ciprofloxacin (CIP). D. J. Wolter, N.D. Hanson, and P.D.Lister. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Beta-lactam MICs and differential expression of blaCMY-2 reflect dual promoter activity. M.D. Reisbig and N.D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Comparison of ampC transcript half-life among three genera of Enterobacteriaceae. B. Abdalhalmid and N. D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Development of a Model System to Determine the Effect of ampD mutations on â-lactam Resistance. 2004. A. J. Schmidtke and N.D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • The First Occurrence of a Pseudomonas aeruginosa in the United States (US) Producing and IMP Metallo-â-lactamase (MBL). N.D.Hanson, A. Hossain, L. Buck, E.S. Moland, and K.S. Thomson. 2004 In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C., 2004
  • Australian Society of Microbiology Antimicrobial Meeting, Queensland Regional Meeting. Morton Bay Research Facility, North Stradbroke Island, Brisbane Australia. July 2004. World Wide Emergence of Beta-lactam Resistance: The Need for Molecular Diagnostics., 2004
  • University of Queensland, Brisbane, Australia: Department of Veterinary Science. July 2004. The Molecular Mechanisms Involved in AmpC-Mediated Resistance: A Complex Process., 2004
  • Australian Society of Microbiology Antimicrobial Meeting, Grand Rounds: Women’s and Children’s Hospital, Adelaide, Australia: July 2004. ESBLs and AmpCs: What’s the Difference?, 2004
  • Australian Society of Microbiology Antimicrobial Meeting, Grand Rounds: Concord Hospital, Sydney Australia: July 2004. ESBLs and Plasmid-mediated AmpC in Gram-Negative Bacteria- What are the differences?, 2004
  • Survey of cefoxitin (FOX) non-wusceptible (NS) E. coli urine isolates (UIs) reveals a high incidence of plasmid-encoded AmpC (pAmpC) â-Lactamase (âL) Producers. 2004. M.D. Reisbig, S.J. Cavalieri, H.A. Hashish, R.V. Goering, and N.D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA., 2004
  • 18. Laboratory Diagnosis of Escherichia coli and Klebsiella spp. producing CTX-M-ß-lactamases. 2004. J. D. D. Pitout, A. Hossain, D. L. Church, N. D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA., 2004
  • Paediatric infection due to multi-resistant Salmonella Infantis carrying blaCMY-2, blaTEM-1, blaCTX-M-15 and blaSHV-5 â-lactamases. 2004. E. Liebana, J. Martinez-Urtaza, M. Batchelor, C. Torres, L. Brinas, L.A. Lagos, B. Abdalhamid, N.D. Nanson, F.A. Clifton-Hadley, R.H. Davies. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA., 2004
  • 16. Evaluation of cefepime (FEP) with and without clavulanic acid (CA) for the detection of ESBLs (Extended Spectrum Beta-Lactamases) in Enterobacteriaceae species. 2004. E. Smith Moland, T.J. Lockkhart, J.A. Black, L.B. Olson, A. HOssain, N.D. Hanson, and K.S. Thomson. In Clinical Microbiology and Infection. 14th European Congress of Clinical Microbiology and Infectious Diseases., 2004
  • Abdalhamid, B. and N. D. Hanson. Differential half-life of the ampC transcript between three genera of Enterobacteriaceae. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri., 2004
  • Schmidtke, A. and N. D. Hanson. AmpD mutations in E. coli. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri., 2004
  • Puerto Rico Veterans Administration Hospital: Infectious Disease Fellows: February 2004. World Wide Emergence of â-lactam and Fluoroquinolone Resistance: The Need for Molecular Diagnostics., 2004
  • University of Puerto Rico, Department of Microbiology and Medical Zoology Graduate Seminar: February 2004. The Complexities of Molecular Mechanisms Involved in AmpC-Mediated Resistance., 2004
  • University of Puerto Rico School of Medicine: Grand Rounds. February 2004. World Wide Emergence of â-lactam and Fluoroquinolone Resistance: The Need for Molecular Diagnostics., 2004
  • Children’s Hospital, Grand Rounds. January 2004. Evolution of Antibiotic Resistance and the Concomitant Decrease in Therapeutic Options for Lung Infections in the Cystic Fibrosis Patient., 2004
  • Emergence of Fluoroquinolone (FQ) Resistant Pseudomonas aeruginosa (PA) in a Cystic Fibrosis (CF) Patient: Discordance between MexEF-OprN and Carbapenem Susceptibility. 2003. D.J. Wolters, J. Black, D. Acquazzino, R. Goering, P.Sammut, N. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, 2003
  • Molecular Analysis of 10 Putative Efflux Genes in Streptococcus pneumoniae (SP) Reveals Widespread Differences Between Wildtype (WT) Strains and Multi-Drug Resistant (MDR) Clinical Isolates. 2003. P.A. Wichman, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, 2003
  • A Novel Mechanism of Resistance to Ciprofloxacin (CIP) and Ethidium Bromide (EB) in Streptococcus pneumoniae (SP): Downregulation of a Putative Permease. 2003. P.A. Wichman, G. A. Perry, K.S. Thomson, N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, 2003
  • Insertional Inactivation of oprD in Clinical Isolates of Pseudomonas aeruginosa Leading to Carbapenem Resistance. 2003. D.J. Wolter, N. Hanson, P. Lister. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation, 2003
  • Prevalence of Plasmid-mediated AmpC beta-lactamases in Klebsiella pneumoniae (KP), Klebsiella oxytoca (KO), Proteus mirabilis (PM), and Salmonella (S) Isolates from 42 ICU and 21 non-ICU Sites in the United States. 2003 J.A. Black, E.Smith Moland, A. Hossain, T.J. Lockhard, L.B. Olson, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • Deletional Analysis of the blaMir-1 Upstream Region Reveals a Novel Promoter Necessary for High-Level Expression and beta-Lactam Resistance. 2003. M. D. Reisbig and N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois, 2003
  • Citrobacter freundii from Canada Producing A Novel CTX-M Gene, blaCTX-M-30. 2003. A. Abdalhamid, J.D.D. Pitout, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • Surveillance for Escherichia coli Producing CTX-M-Type ƒÒ-Lactamases in the Calgary Health Region (CHR). 2003. J.D.D. Pitout, K.B. Laupland, D.L. Church, S. Elsayed, D. Gregson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • Detection of CTX-M-Like ESBLs in Thirteen States within the USA. 2003. E.S. Moland, J.A. Black, K.S. Thomson, N.D. Hanson, T. J. Lockhart, L.B. Olson, A. Hossain., 2003
  • Characterisation of Beta-lactamases Responsible for Resistance to Extended-Spectrum Cephalosporins in E. coli and S. enterica from U.K. Food Animals. 2003. E. Liebana, M. Gibbs, C. Clouting, L. Barker, F. Clifton-Hadley, E. Pleydell, B. Abdalhamid, N. Hanson, L. Martin, C. Poppe, R. Davies. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • E. coli producing KPC-3 carbapenem hydrolyzing enzyme (CHE). 2003. T. Hong, E.S. Moland, B. Abdalhamid, N.D. Hanson, J. Wang, C. Sloan, D. Fabian, A. Farajallah, J. Levine, K.S. Thomson. 2003. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • Prevalence of ESBLs in the United States. 2003. E. Smith Moland, J.A. Black, N.D. Hanson, A. Hossain, B. Abdalhamid, W. Song, T.J. Lockhart, L.B. Olson, K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • Occurrence of a CTX-M-1-like ESBL in a U.S. Isolate of Citrobacter freundii (CF). 2003. S.E. Sharp, C. Suarez, E. Smith Moland, A. Hossain, N.D. Hanson, and K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • A New Quality Control Strain for Routine Testing for Production of Extended Spectrum Beta-Lactamases (ESBL). 2003. J.E. Mortensen, M. Bernier, L. Gray, S. Doland, E.S. Moland, B. Abdalhamid, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • First Report of Plasmid-encoded (PE) Carbapenem Hydrolyzing Enzyme (CHE) KPC-2 in Enterobacter cloacae (EC). 2003 A. Hossain, M.J. Ferraro, R.M. Pino, R.B. Dew III, E.S. Moland, T.J. Lochart, K.S. Thomson, R.V. Goering, and N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2003
  • A. Hossain, Reisbig. M.D., and N.D. Hanson. High-level expression of the plasmid-encoded AmpC gene, blaCMY-7 does not compromise the virulent phenotype of a strain of Salmonella typhimurium. In Abtracts of the 13th European Congress of Clinical Microbiology aand Infectious Disease, Glasgow, United Kingdom, 2003
  • M.D. Reisbig and N.D. Hanson. Variations in â-Lactam Susceptibilities Between Organisms Expressing the Plasmid-Encoded AmpC beta-lactamase CMY-2 is Attributed to Variable Gene Expression. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, 2003
  • Daniel J. Wolter, Nancy D. Hanson, and Philip D. Lister. Multi-Drug Resistance Associated with mexXY Expression in Clinical Isolates of Pseudomonas aeruginosa from a Texas Hospital. In Abstracts of the 13th Congress of Clinicacl Microbiology and Infectious Diseases, Glasgow, United Kingdom, 2003
  • A. Hossain. P. Wickman, K. S. Thomson and N.D. Hanson Molecular analysis of Streptococcus pneumoniae mutants selected by DK-507k, an investigational fluoroquinolone. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, 2003
  • D WOLTER, M. REISBIG, N. HANSON, P. LISTER. Pharmacodynamics of Cefepime-Aztreonam Combination against Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients. In Abstracts of the 13th European Congresss of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom, 2003
  • P.A. Wickman*, A. Hossain, K.S. Thomson, and N.D. Hanson Differences in selection of efflux-mediated fluoroquinolone resistance in penicillin-susceptible and -resistant Streptococcus pneumoniae after repeated exposure to ciprofloxacin and moxifloxacin. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom., 2003
  • Oklahoma State University: Stillwater Oklahoma. October 28, 2002. The Complexities of Molecular Mechanisms Involved in AmpC Beta-lactamase-mediated Resistance, 2002
  • Discovery of CTX-M-like ESBLs in E. coli Isolates from Five States in the USA. 2002. E. Smith Moland, S. Pottumarthy-Boddu, J.A. Black, A. Hossain, N.D. Hanson, K.S. Thomson. In Abstracts Addendum of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., 2002
  • Pitout, J.D., E.Smith-Moland, S. Elsayed, N. Hamilton, J. Conly, D. Church, N. Hanson. 2002. A Novel Carbapenem-Hydrolyzing Enzyme (CHE) Produced by an Enterobacter cloacae Isolate from Canada. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., 2002
  • Wolter, D. J., N.D. Hanson, and P. D. Lister. 2002. Continued Expression of mexCD-oprJ Among Phenotypic Revertants of Pseudomonas aeruginosa (PA) that Have Lost Their Fluoroquinolone Resistance. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., 2002
  • Wolter, D. J., T. J. Lockhart, N.D. Hanson, and P.D. Lister. 2002. Imipenem Hypersusceptibility Among mexCD-oprJ Hyperexpressing Mutants of Pseudomonas aeruginosa does not Involve Decreased expression of ampC or Increased Expression of oprD. In Abstracts of the 42nd Interscience, 2002
  • Hossain, A., E.S. Moland, J.A. Black, N.D. Hanson, K.S. Thomson. 2002. DQ-113: In Vitro development and Mutational Analysis of Resistance in Staphylococcus aureus, Penicillin Resistant Streptococcus pneumoniae (PRSP) and Vancomycin Resistant Enterococci (VRE). In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., 2002
  • Reisbig, M.D. and N.D. Hanson. 2002. Therapeutic Implications for the Plasmid-Encoded (PE) AmpC beta-Lactamase, ACT-1, Expressed in ampD- E. coli. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA., 2002
  • University of Kansas, St. Lukes Hospital. October 15, 2002. ESBLs and AmpC Beta-lactamases: What's the Difference, 2002
  • ESBLs and AmpC beta-lactamases: What’s the Difference? 1. Irish Society of Clinical Microbiology: Dublin Ireland Invited Speaker, 2002
  • Great Plains State Society for Molecular Biology and Genetics: Omaha, Nebraska: June 2002. Invited speaker “AmpC-mediated resistance in Gram-negative bacteria: Questions but not many answers.”, 2002
  • American Society of Microbiology Symposium Speaker: Salt Lake City, Utah, USA: May 2002. “AmpC beta-Lactamases: A Conundrum.”, 2002
  • Wolter, D.J., N.D. Hanson, G. Haynatzki, and P.D. Lister. 2002. Efflux-Mediated Resistance Among Pseudomonas aeruginosa: Complex Regulation of a Complex Resistance Mechanism. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., 2002
  • Reisbig, M.D. and N.D. Hanson. 2002. The Role of Gene Copy Number in Overall Expression of ampC Genes of Enterobacter cloacae Origin. The 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., 2002
  • Morrow, S.S. and N.D. Hanson. 2002. Differentiation of Multiple SHV or FOX Genes Using Denaturing High Performance Liquid Chromatography. 2002. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., 2002
  • Wickman, P.A., A. Hossain, K.S. Thomson, and N.D. Hanson. 2002. Moxifloxacin has Reduced Potential to Select Mutational Fluoroquinolone Resistance in Streptococcus pneumoniae. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., 2002
  • Moland, E.S., K.K. Sandu, M.R. Pincus, J.A. Black, M.D. Reisbig, N.D. Hanson, K.S. Thomson. 2002. A Simple Phenotypic Approach to the Detection of Inducible Plasmid-mediated AmpC -lactamse (pAmpC) Production in Two New York Isolated of Klebsiella pneumoniae (KP). In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah., 2002
  • Moland, E.S., J. Johnson, J.A. Black, T.J. Lockhart, A. Hossain, V.L. Herrera, R.V. Goering, N.D. Hanson, and K.S. Thomson. 2001. Klebsiella pneumoniae (KP) Isolates Producing a Carbapenem Hydrolyzing Enzyme (CHE). In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Coudron, P.E., S.M. Tallent, E.S. Moland, N.D. Hanson, M.B. Edmond, R.P. Wenzel. 2001. Occurrence of Extended-Spectrum (ESBL) and AmpC Beta-Lactamases (BLs) in U.S. Bacteremic Isolates of Klebsiella pneumoniae (Kp): Two Isolates Harbor Inducible Plasmid-Mediated ACT-1-Like BLs. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Moland, E.S., T.J. Cleary, M.D. Reisbig, Y. Jiang, P.E. Coudron, T.J. Lockhart, N.D. Hanson, K.S. Thomson. 2001. Occurrence of Inducible Plasmid-mediated AmpC -lactamase (ipAmpC), DHA-1, in a Miami Isolate of Klebsiella pneumoniae: New Implications for Susceptibility Testing? In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Hossain, A., E.S. Moland, J.A. Black, S.A. Chartrand, N.D. Hanson, K.S. Thomson. 2001. A New Fluoroquinolone (FQ) With a Low Frequency of Mutational Resistance in MRSA. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Herrera, V.L. and N.D. Hanson. 2001. Complex Expression of Novel Plasmid-mediated AmpC -Lactamase Gene. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois.Chicago, Illinois., 2001
  • Jiang, Y., E.S. Moland, Y.Ni, N.D. Hanson. 2001. Novel Mutations in the Promoter and Attenuator Regions of Hyperproducing AmpC E. coli strains from China. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Hanson, N.D., S.A. Neville, I.B. Gosbell, A. Hossain, E.S. Moland, and K.S. Thomson. 2001. Salmonella enterica serotype Typhimurium producing CMY-7, SHV-9 and OXA-30 -Lactamases. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Reisbig, M.D. and N.D. Hanson. 2001. The Plasmid-mediated AmpC -Lactamase, ACT-1, is Inducible in a Multiply Resistant Klebsiella pneumoniae Isolate. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois., 2001
  • Mahlen, S.D. and N.D. Hanson. 2001. The Stem-Loop Structure in the 5’Untranslated Region (5’UTR) of the ampC Transcript of Serratia marcescens is Involved in Transcript Stability. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation given by N.D. Hanson., 2001
  • American Soceity for Microbiology Regional Meeting. Analysis of the 5' flanking region of a novel plasmid-mediated amp'c beta-lactamase, 2001
  • American Soceity of Microbiology Regional Meeting. Deletion of secondary structure in the 5' untranslated region of the ampC gene of Serratia marcescens results in a decrease in translational efficiency, 2001
  • American Society for Microbiology Regional Meeting. Inverse relationship in the expression of multi-drug efflux pumps, 2001
  • American Society for Microbiology Regional Meeting. Molecular and phenotypic analysis to determine the influence of moxifoxacin and ciprofloxacin in selecting mutational fluoroquinolone resistance in Streptococcus pneumoniae, 2001
  • American Society for Microbiology Regional Meeting. PCR amplification of the genetically diverse ampC genes of Enterobacter cloacae using the proof-reading enzyme, Pwo, 2001
  • American Society for Microbiology Regional Meeting. The plasmid-mediated AmpC beta-lactamase, ACT-1, is inducible, 2001
  • Regional Medical Student Research Forum. Evaluation of Nucleotide Diversity within Pseudomonas aeruginosa ampC beta-lactamase, 2001
  • University of Nebraska at Lincoln.Graduate Seminar Speaker."The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae.", 2001
  • Regional AAAS meeting. Analysis of the 5' flanking region of the plasmid-mediated ampC gene, ACT-1 reveals an Enterobacter clacae ampR binding sight and an ampR gene., 2000
  • University of Dublin, Trinity College, Ireland: Annual molecular medicine symposium, Keynote speaker microbial genetics. Title: "The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae.", 2000
  • Medical School of Edinburgh, Scotland "The regulation of AmpC B-Lactamase expression in Enterobacteriaceae and its relationship to resistance.", 2000
  • St. James Hospital, Dublin, Ireland"The regulation of AmpC B-Lactamase expression in Enterobacteriaceae and its relationship to resistance.", 2000
  • University of Nebraska at Omaha.Graduate Seminar Speaker."The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae.", 2000
  • 40th Interscience Conference on Antimicrobial Agents and Chemotherapy. toronto Canada. A Novel Growth-Phase Dependent Factor that Binds to the Serratia marcescens ampC gene and correlates with a Decrease in ampC Transcription, 2000
  • Identification, Cloning and Sequencing of a Novel FOX Plasmid-Mediaated AmpC, N.D. Hanson, P. Coudron, E.S. Moland and C.C. Sanders 39th ICAAC. San Francisco, 1999
  • Sequence Analysis of the ampC and ampR Regions of Serratia marcescens Reveals a Unique 5' Untranslated Region in ampC. S.S. Morrow, C.C. Sanders, and N.D. Hanson 39th ICAAC San Francisco,, 1999
  • Molecular Characterization of Mutants Responsible for Dichotomous Fluoroquinolone Resistance in Staphlococcus aureus, 39th ICAAC, San Francisco, 1999
  • Detection and Characterization of the Beta-Lactamases Produced by Citrobacter koseri, ES Moland, KS Thomson, C.C. Sanders, N.D. Hanson, 39th ICACCA San Francisco, 1999
  • Differential Induction of the Chromosomal Beta-Lactamase Gene of Seratia marcescens by beta-Lactam Antibiotics, Missouri Valley Regional ASM, Tulsa, OK;, 1999
  • Cloning and sequencing of the chromosomally encoded ampC and ampR genes of Serratia marcescens, Missouri Valley Regional ASM, Tulsa, OK,, 1999
  • Transcriptional analysis of Serratia marcescens ampC, Mahlen, S.D. C.C. Sanders, and N.D. Hanson,Southwestern and Rocky Mountain Division American Association for the Advancement of Science, Creighton University, Omaha, NE, 1999

Research and Scholarship

Research and Scholarship Interests

  • Our laboratory is interested in the molecular mechanisms of antibiotic resistance, both chromosomal and plasmid-mediated, in Gram-negative pathogens such as Escherichia coli, Klebsiella pneumoniae, Salmonella spp., and Pseudomonas aeruginosa. We are especially interested in mechanisms involved in the regulation of gene expression required for the expression of plasmid-encoded resistance genes and how chromosomal encoded factors play a role in the expression of those genes.  Our laboratory also evaluates mechanisms involved in the emergence of P. aeruginosa resistance associated with cystic fibrosis patients. Another area of active research involves the development of PCR-based techniques for the molecular detection of genes encoding extended-spectrum beta-lactamases, plasmid-mediated AmpC beta-lactamases, and carbapenemases in clinical isolates.

Current Research Projects

Awards and Honors

  • Divisional: PRIMERS FOR USE IN DETECTING METALLO-BETA LACTAMASES (Patent No: PCT/US2007/012629), 2007
  • MULTIPLEX PCR FOR THE DETECTION OF AMPC BETA-LACTAMASE GENES (Patent No: 7045291), 2006
  • National Stage PCT - PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: PCT/US 2004/029695), 2006
  • DIVISIONAL - MULTIPLEX PCR FOR THE DETECTION OF AMPC BETA-LACTAMASES (Patent No: 11/302,037), 2005
  • Outstanding service as a Branch Councilor, American Society for Microbiology , 2005
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES CIP (Patent No: 6905898), 2005
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: 6893846), 2005
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: pct/us2004/029695), 2004
  • RAPID NUCLEIC ACID ISOLATION METHOD AND COMPOSITIONS (Patent No: pct/us2004/023269), 2004
  • Received a one month travel award for the promotion of research to the University of Queensland, Brisbane Australia., 2004
  • NATIONAL STAGE PCT - PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: PCT/US2004/029695), 2004
  • PRIMERS FOR DETECTING BETALACTAMASES (Patent No: 60/502,885), 2003
  • PRIMERS FOR DETECTING BETALACTAMASES (Patent No: 60/502,091), 2003
  • MATERIALS AND METHODS FOR USE IN MICROBIOLOGY AND ESPECIALLY IN AGAR BASED SYSTEMS (Patent No: 60/490,229), 2003
  • METHODS AND MATERIALS FOR USE IN MICROBIOLOGY AND ESPECIALLY IN BROTH-BASED SYSTEMS (Patent No: 60/490,353), 2003
  • RAPID NUCLEIC ISOLATION METHOD AND COMPOSITIONS THEREOF (Patent No: 60/489,017), 2003
  • Primers for Use in Detecting Beta-Lactamases (Patent No: 10/318,970), 2002
  • MULTIPLEX PCR FOR THE DETECTION OF ampC BETA-LACTAMASE GENES (Patent No: 10/147,601), 2002
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: 60/340,466), 2001
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES. (Patent No: 6242223), 2001
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES. (Patent No: 09/814,252), 2001
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES. (Patent No: 09/814,257), 2001
  • PRIMERS FOR USE IN DETECTING BETA-LACTAMASES (Patent No: 09/407,818), 1999