Peter W. Abel, PhD
Peter W. Abel, PhD

Peter W. Abel, PhD

Professor
School of Medicine

Academic Appointments

Department

  • Pharmacology

Position

  • Professor

Secondary Appointment

  • School of Pharmacy and Health Professions

Education

  • University of Wisconsin, B.S. Pharmacy, 1968-1973
  • West Virginia University, Ph.D. Pharmacology, 1975-1978
  • University of Iowa, Postdoctoral Pharmacology/Neurosurgery, 1979-1982

Publications and Presentations

Articles

  • Jiang H1, Xie Y, Abel PW, Wolff DW, Toews ML, Panettieri Jr RA, Casale TB, Tu Y. RGS2 Repression Exacerbates Airway Hyperresponsiveness and Remodeling in Asthma., American Journal of Respiratory Cell Molecular Biology, 12, 3190, 2014
  • Peter W. Abel, Cameron M. Kieffer. Pulmonary Hypertension., Biomedical Sciences, 11-14, 5255, 2014
  • Peter W. Abel, Cameron M. Kieffer. Hyperkalemia., Biomedical Sciences, 10-14, 5069, 2014
  • Smith, D. David; Gallagher, Audrey T.; Crowley, Vincent M.; Gergens, Wayne M.; Abel, Peter W.; Hulce, Martin: An Efficient Synthesis of 4(5)-Benzyl-l-histidines Employing Catalytic Transfer Hydrogenolysis at Elevated Temperatures, Synthesis, 2014, Vol 4, 515, 2014
  • Xie Y, Abel PW, Kirui JK, Deng C, Sharma P, Wolff DW, Toews ML, Tu Y. (2013) Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion., Biochem Pharmacol, 85, 2013
  • Xie Y, Abel PW, Kirui JK, Deng C, Sharma P, Wolff DW, Toews ML, Tu Y. Identification of upregulated phosphoinositide 3-kinase ã as a target to suppress breast cancer cell migration and invasion., Biochem Pharmacol, 85, 1454, 2013
  • Yan Xie, Haihong Jiang, Hoai Nguyen, Shuping Jia, Abdo Berro, Reynold A. Panettieri, Dennis W. Wolff, Peter W. Abel, Thomas B. Casale, Yaping Tu. Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness., Journal of Allergy and Clinical Immunology, 2012
  • Haihong Jiang, Yan Xie, Peter W. Abel, Myron L. Toews, Robert G. Townley, Thomas B. Casale, and Yaping Tu. Targeting Phosphoinositide 3-Kinase g in Airway Smooth Muscle Cells to Suppress Interleukin-13-Induced Mouse Airway Hyperresponsiveness., Journal of Pharmacology and Experimental Therapeutics, 342:, 305-311, 2012
  • Horiba, M, Qutna N, Gendapodi,P, Agrawal S, Sapkota N, Abel P, Townley RG (2011) Effect of IL-1â and TNF-ávs IL-13 on bronchial hyperresponsiveness, â2-adrenergic responses and cellularity of bronchial alveolar lavage fluid, Autonomic and Autacoid Pharmacology, 31, 37-39, 2012
  • Abel PW, Jain N. (2011) Alpha adrenoceptor assays., Not Applicable, 5, 4-15 to 4-39, 2012
  • Smith DD, Gallagher AT, Gergens W, Crowley VM, Abel PW, Hulce M. (2011) Optimizing the Synthesis of 4(5)-Benzyl-L-Histidine and Analogues., Peptides: The Wave of the Future, 22, 34-35, 2011
  • Wong CY, Wuriyanghan H, Xie Y, Lin MF, Abel PW, Tu Y. Epigenetic Regulation of Phosphatidylinositol 3,4,5-Triphosphate-dependent Rac Exchanger 1 Gene Expression in Prostate Cancer Cells., J Biol Chem, 286, 25813-25822, 2011
  • Wolff DW, Xie Y, Deng C, Gatalica Z, Yang M, Wang B, Wang J, Lin MF, Abel PW, Tu Y.Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth., Int. J. Cancer, 2011, 15, 2011
  • Wang J, Xie Y, Wolff DW, Abel PW, Tu Y. DHHC protein-dependent palmitoylation protects regulator of G-protein signaling 4 from proteasome degradation., FEBS Lett., 584, 4570-4574, 2010
  • Jiang H, Abel PW, Toews ML, Deng C, Casale TB, Xie Y, Tu Y. Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations., Journal of Pharmacology and Experimental Therapeutics, 333, 703-709, 2010
  • Kirui JK, Xie Y, Wolff DW, Jiang H, Abel PW, Tu Y. G{beta}{gamma} signaling promotes breast cancer cell migration and invasion. J Pharmacol Exp Ther. 333: 393-403, 2010., Journal of Pharmacology and Experimental Therapeutics, 333, 393, 2010
  • Xie, Y, Wolff, DW, Wei, T, Wang, B, Kirui, J, Jiang, H, Qin, J, Abel, PW. Tu, Y. Breast Cancer Migration and Invasion Depend on Proteasome Degradation of Regulator of G-protein Signaling 4., Cancer Research, 2009
  • Robert G. Townley, RG, Gendapodi, PR, Qutna,N, Evans, J, Romero, FA, Abel, PW. Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of â-adrenergic bronchodilators and corticosteroids., Annals of Allergy, Asthma & Immunology, 2009
  • Yao, M, Abel, PW. Salcatonin, Xpharm (web based), 2008
  • Smith, DD, Abel, PW. Calcitonin Gene-Related Peptide, Xpharm (web based), 2008
  • Taylor, CK, Abel, PW, Hulce, M, Smith DD. N-terminal bis-(2-chloroethyl)amino and fluorosulphonyl analogues of calcitonin gene-related peptide(8-37): irreversible antagonists at calcitonin gene-related peptide receptors, Chemical Biology and Drug Design, 70, 216, 2007
  • Smith, RC, McClure, MC, Smith, MA, Abel, PW, Bradley, ME. The role of voltage gated potassium channels in the regulation of mouse uterine contractility, Reproductive Biology and Endocrinology, 5, 41, 2007
  • Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM. Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii, Peptides, 28, 505, 2007
  • Taylor, CK, Smith DD, Hulce, M and P W Abel. Pharmacological characterization of novel CGRP receptor peptide antagonists that are selective for human CGRP receptors., Journal of Pharmacology and Experimental Therapeutics, 319, 749-757, 2006
  • Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM. Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii., Peptides, 28, 505-514, 2006
  • Taylor, CK and Abel, P.W.: Compound 3, Xpharm (web based), 2006
  • Taylor, CK and Abel, P.W.: BIB, Xpharm (web based), 2006
  • Taylor, CK and Abel, P.W.: Human beta CGRP, Not Applicable, 2006
  • Rorabaugh, B and Abel, P.W.: Amedulin, Xpharm (web based), 2006
  • Taylor, CK, Smith DD, Hulce, M and P W Abel. Pharmacological characterization of novel CGRP receptor peptide antagonists that are selective for human CGRP receptors., Journal of Pharmacology and Experimental Therapeutics, 2006
  • Abel, P.W. and Rorabaugh, B: Ephedrine, Not Applicable, Xpharm, 2005
  • Abel, PW: Isoproterenol, Xpharm (web based), 2005
  • Abel, PW and Taylor, CK: Compound 1, Xpharm (web based), 2005
  • Abel, PW, Taylor, CK: BIBN, Xpharm (web based), 2005
  • Abel, P.W. and Rorabaugh, B:Adrenomedulin, Not Applicable, 2005
  • Taylor, CK and Abel, P.W.: Human alpha CGRP 8-37., Xpharm (web based), 2005
  • Abel, PW and Smith, DD AC-187, Xpharm (web based), 2005
  • Conlon, JM, Jouenne, T, Coquet, L, Cosquer, D, Vaudry, H, Taylor, CK and Abel, PW. Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei., General and Comparative Endocrinology, 2005
  • Taylor, C.K., P.W. Abel, M. Hulce, D.D. Smith. Solvent effects on coupling yields during rapid solid phase synthesis of CGRP(8-37) employing in situ neutralization., Journal of Peptide Research, 65, 84-89, 2005
  • Smith, R.C., M.C. McClure, P.W. Abel, M.E. Bradley. Expression of voltage activated potassium channels., American Journal of Physiology Cell Physiology, 2005
  • Bockman, C.S., Michael R. Bruchas, Wanyun Zeng, Kelly A. O'Connell, Peter W. Abel, Margaret A. Scofield, and Frank J. Dowd. Submandibular Gland Acinar Cells Express Multiple Alpha-1 Adrenoceptor Subtypes., Journal of Pharmacology and Experimental Therapeutics, 2004
  • Abel, P.W., M.T. Piascik. Introduction to Autonomic Nervous System Drugs. In Pharmacology and Therapeutics for Dentistry. Yagelia, Dowd, Neidle (eds), Elsevier, Mosby, Not Applicable, 5th Edition, 84-97, 2004
  • Abel, P.W., M.T. Piascik. Adrenergic Agonists. In Pharmacology and Therapeutics for Dentistry. Yagelia, Dowd, Neidle (eds), Elsevier, Mosby, Not Applicable, 5 th Edition, 98-112, 2004
  • Abel, P.W., M.T. Piascik. Adrenergic Blocking Drugs. In Pharmacology and Therapeutics for Dentistry. Yagelia, Dowd, Neidle (eds), Elsevier, Mosby, Not Applicable, 5th Edition, 113-124, 2004
  • Bockman, C.S. and P.W.Abel. Drugs of Abuse. In Pharmacology and Therapeutics for Dentistry. Yagelia, Dowd, Neidle (eds), Elsevier, Mosby, Not Applicable, 5 th Edition, 814-828, 2004
  • Bockman CS, PW Abel. Drugs of Abuse. In Pharmacology and Therapeutics for Dentistry., Not Applicable, 814-828, 2004
  • Taylor, CK, PW Abel, DD Smith. NMP is unsuitable as a solvent for synthesis of CGRP., Not Applicable, 203-204, 2004
  • Smith DD, PW Abel. Calcitonin gene related peptide., Xpharm (web based), 2004
  • O'Donohue, HA, PW Abel, CS Bockman. Pharmacological properties of serotonin receptor subtypes in the artery., Archives of Oral Biology, 49, 223-232, 2004
  • : Smith DD, Saha S, Fang G, Schaffert C, Waugh DJ, Zeng W, Toth G, Hulce M, Abel PW. Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity., Not Applicable, 46, 2003
  • : Hague C, Gonzalez-Cabrera PJ, Jeffries WB, Abel PW. Relationship between alpha(1)-adrenergic receptor-induced contraction and extracellular signal-regulated kinase activation in the bovine inferior alveolar artery., Journal of Pharmacology and Experimental Therapeutics, 303, 403, 2002
  • : Jiao X, Gonzalez-Cabrera PJ, Xiao L, Bradley ME, Abel PW, Jeffries WB. Tonic inhibitory role for cAMP in alpha(1a)-adrenergic receptor coupling to extracellular signal-regulated kinases 1/2., Journal of Pharmacology and Experimental Therapeutics, 303, 247, 2002
  • Alpha-1 ERK, FASEB Journal, 16, A563, 2002
  • , Journal of Pharmacology and Experimental Therapeutics, 299 #3, 1086-1094, 2001
  • , Proceedings of the European Peptide Symposium, 2001
  • Effects of Trout Endothelin on the motility of gastrointestinal smooth muscle from the trout and rat, General and Comparative Endocrinology, 123, 156, 2001

Publications

  • Haihong Jiang,Yan Xie,Peter Abel,Dennis Wolff,Myron Toews,Reynold Panettieri, Thomas Casale,Yaping Tu. RGS2 Repression Exacerbates Airway Hyperresponsiveness and Remodeling in Asthma., FASEB Journal, 29, 775.10, 2015
  • Chuu-Yun Wong, Yan Xie, Peter Abel, Margaret Scofield and Yaping Tu PMA suppresses breast cancer cell proliferation via PKCε-mediated P-Rex1 downregulation, FASEB Journal, 28, 1148, 2014
  • Robert Townley, Pradeep Gendapodi,Swati Agrawal, Yang Wang, Tony Romero, and Peter Abel, Preclinical and Clinical Findings: Role Of Periostin, IL-13, Lebrikzumab and Corticosteroid Resistance, World Allergy Organization Journal, 2013, 5842, 2013
  • Chuu-Yun A. Wong, Yan Xie, Dennis W. Wolff, Peter W. Abel, Yaping Tu. PKC epsilon-mediated P-Rex1 downregulation suppresses breast cancer cell proliferation., FASEB Journal, 27, 1096.10, 2013
  • Yan Xie, Haihong Jiang, Peter W. Abel, Thomas B. Casale, Reynold A. Panettieri, Yaping Tu. RGS2 repression increases susceptibility of mice to interleukin- 13-induced airway hyperresponsiveness., FASEB Journal, 27, 1095.8, 2013
  • Neha Jain, Yaping Tu, Peter W Abel. Effects of hypoxia on regulators of G-protein signaling 2 (RGS2) regulation of pulmonary arterial constriction., FASEB Journal, 27, 1141.3, 2013
  • Neha Jain, Yaping Tu, Peter W Abel. Effects of hypoxia on regulators of G-protein signaling 2 (RGS2) regulation of pulmonary arterial constriction., Midwest Student Biomedical Research Forum, 2013
  • Abstracts of the American Chemical Society meeting, Omaha, NE, November, 2012., Not Applicable, 2012
  • Neha Jain, Yaping Tu and Peter W Abel Regulator of G Protein Signaling 2 (RGS2) regulates pulmonary vasoconstriction, FASEB Journal, The FASEB Journal. 2012;26:842.9, 2012
  • Haihong Jiang, Yan Xie, Peter W. Abel, Myron L. Toews, Robert G. Townley, Thomas B. Casale and Yaping Tu. Targeting phosphoinositide 3-kinase in airway smooth muscle cells to suppress interleukin-13-induced mouse airway hyperresponsiveness, FASEB Journal, The FASEB Journal. 2012;26:667.4, 2012
  • Neha Jain, Yaping Tu and Peter W Abel. Regulator of G Protein Signaling 2 (RGS2) regulates pulmonary vasoconstriction., Midwest Student Biomedical Research Forum, 45, 2012
  • Smith DD, Gallagher AT, Gergens W, Crowley VM, Abel PW, Hulce M. 4(5)-Benzyl-L-Histidine and Analogues., Peptides: Proceedings of the American Peptide Society, 2011
  • Chuu-Yun A Wong, Da Ha, Yan Xie, Dennis W Wolff, Peter W Abel, and Yaping Tu Protein kinase C (PKC) regulates phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 (P-Rex1) gene expression through a histone deacetylase interaction with Sp1 in prostate cancer., FASEB Journal, 25, 1090, 2011
  • Haihong Jiang, Peter W Abel, Myron L Toews, Caishu Deng, Thomas B Casale, Yan Xie, and Yaping Tu G{beta}{gamma}-activated phosphoinositide 3-kinase {gamma} regulates airway smooth muscle contraction by modulating calcium oscillations., FASEB Journal, 25, 1011, 2011
  • Yaping Tu, Yan Xie, Dennis W. Wolff, Joseph K. Kirui, Haihong Jiang, Caishu Deng, and Peter W. Abel Targeting G protein-coupled receptor signaling to suppress breast cancer metastasis, FASEB Journal, 25, 802, 2011
  • Yan Xie, Jincheng Wang, Dennis W. Wolff, Peter W Abel, and Yaping Tu DHHC protein-dependent palmitoylation protects regulator of G-protein signaling 4 from proteasome degradation, FASEB Journal, 25, 802, 2011
  • Dennis W. Wolff, Yan Xie, Zoran Gatalica, Mingjie Yang, Bo Wang, Jincheng Wang, Ming-Fong Lin, Peter W. Abel, and Yaping Tu 5-aza-2'-deoxycytidine suppresses androgen independent prostate cancer growth by restoring RGS2 expression, FASEB Journal, 25, 802, 2011
  • Chuu-Yun Anny Wong, Da Ha, Yan Xie, Dennis W. Wolff, Peter W. Abel and Yaping Tu - Histone Acetylation Up-regulates Phosphatidylinositol-3,4,5-triphosphate-dependent Rac Exchange Factor 1 (P-Rex1) Expression to Promote Prostate Cancer Metastasi, FASEB Journal, 24, 964.7, 2010
  • Joseph K Kirui, Yan Xie, Dennis W Wolff, Haiong Jiang, Peter W Abel and Yaping Tu - Gâ Signaling Promotes Breast Cancer Cell Migration and Invasion, FASEB Journal, 24, 964.16, 2010
  • Effect of cooling on alpha 2 adrenoceptors, FASEB Journal, 302, 2009
  • Problem based teaching in a large classroom setting for on-campus and off-campus students, FASEB Journal, 2009
  • Witt, K, Brauer, PR, Abel, PW, Scofield, MA. Identification of a Rat RAMP2 isoform. The role of native signal peptides in trafficking RAMP2 to the plasma membrane, FASEB Journal, 21, 569, 2008
  • Smith, D, Taylor, CK, Abel, PW, Hulce, MR. N-terminal irreversible antagonists of calcitonin gene-related peptide(8-37)., Proceedings of the European Peptide Symposium, 8, 37, 2008
  • Bockman, CS, Bruchas, MR, O'Connell, K, Abel, PW. Characterization of the alpha-1 adrenoceptor subtype and its signaling pathway for activation of ERK1/2 in submandibular gland acinar cells. FASEB Journal 20: #5, A225., Federation of American Societies for Experimental Biology, 20, A225, 2007
  • Witt, K, Rorabaugh, B, Abel, PW, Scofield, M. Identification of a Rat RAMP2 isoform. FASEB Journal 20: #5, A695., Federation of American Societies for Experimental Biology, 20, A695, 2007
  • Smith, D, Taylor, CK, Abel, PW, Hulce, MR Competitive and irreversible antagonists of CGRP. Proceedings of the American Peptide Society., Proceedings / Workshops, 2007
  • Smith, R, O'Connell, K, Igwike, G, Rice, A, Abel, PW, Bradley, ME. Expression of two pore-domain potassium channels in mouse myometrium. FASEB Journal 20: #5, A237., Not Applicable, 20, 2007
  • Taylor, CK, Smith DD, Hulce, M and P W Abel. Pharmacological characterization of novel high affinity CGRP receptor antagonists that are selective for human CGRP receptors. FASEB Journal 20: #5, A665., Not Applicable, 20, 2007
  • Witt, k, Rorabaugh, B, Abel, PW, Scofield, M. Identification of a Rat RAMP2 isoform., FASEB Journal, 20, #4, A695, 2006
  • Taylor, CK, Smith DD, Hulce, M and P W Abel. Pharmacological characterization of novel high affinity CGRP receptor antagonists that are selective for human CGRP receptors., FASEB Journal, 20 #4, A665, 2006
  • Smith, R, O'Connell, K, Igwike, G, Rice, A, Abel, PW, Bradley, ME. Expression of two pore-domain potassium channels in mouse myometrium., FASEB Journal, 20 #4, A237, 2006
  • Bockman, CS, Bruchas, MR, O'Connell, K, Abel, PW. Characterization of the alpha-1 adrenoceptor subtype and its signaling pathhway for for activation of ERK1/2 in submandibular gland acinar cells., FASEB Journal, 20 #4, A225, 2006
  • Taylor, CK, Smith DD, Abel, PW: Pharmacological Characterization of Irreversible Antagonists of Calcitonin Gene-Related Peptide Receptors, FASEB Journal, 19 , A105, 2005
  • Smith RC, McClure, MC, Smith, MA, Abel, PW, Bradley, ME: 4-AP contraction and Kv channel expression in mouse myometrium, FASEB Journal, 19, A538, 2005
  • Taylor, CK, PW Abel, DD Smith Synthesis and pharmacological characterization of CGRP(8-37) analogues, FASEB Journal, 18, A597, 2004
  • Bruchas MR, CS Bockman, ML Toews, PW Abel. Alpha-1 AR couples to ERK in a submandibular gland cell line, FASEB Journal, 18, A214, 2004
  • Sith, RC, MC McClure, PW Abel, ME Bradley. Expression of voltage activated potassium channels., FASEB Journal, 18, A598, 2004
  • Serotonin Receptors, FASEB Journal, 16, A935, 2002
  • Alpha-1 in salivary glands, FASEB Journal, 16, 2002
  • LPS and alpha-1, FASEB Journal, 16, A564, 2002
  • CGRP Taylor antagonist, FASEB Journal, 16, A189, 2002
  • CGRP Boyd, FASEB Journal, 16, A576, 2002
  • Age related changes in alpha-1 adrenergic receptor reserve., FASEB Journal, 2001
  • CGRP receptor signaling pathways in SK N MC cells and HEK 293 cells, FASEB Journal, 2001
  • Reduced submandibular gralnd muscarinic receptors in a mouse ACHE knockout model, Journal of Dental Research, 80, 859, 2001

Presentations

  • Effects of hypoxia on regulators of G-protein signaling 2 (RGS2) regulation of pulmonary arterial constriction., 2013
  • FASEB - April 2012. Targeting phosphoinositide 3-kinase in airway smooth muscle cells to suppress interleukin-13-induced mouse airway hyperresponsiveness., 2012
  • FASEB - April, 2012. Regulator of G Protein Signaling 2 (RGS2) regulates pulmonary vasoconstriction., 2012
  • Midwest Student Research Forum - March 2012. Regulator of G Protein Signaling 2 (RGS2) regulates pulmonary vasoconstriction., 2012
  • D. David Smith, Audrey T. Gallagher, Wayne Gergens, Peter W Abel, Martin Hulce. Analogues of 4-benzyl-L-histidine for structure activity studies of a CGRP antagonist. 45th ACS Midwest Regional Meeting, 2010
  • Problem based teachinng in a large classroom setting, 2009
  • Witt, K, Brauer, PR, Abel, PW, Scofield, MA. Identification of a Rat RAMP2 isoform. The role of native signal peptides in trafficking RAMP2 to the plasma membrane, 2008
  • Smith, D, Taylor, CK, Abel, PW, Hulce, MR. N-terminal irreversible antagonists of calcitonin gene-related peptide(8-37), 2008
  • Smith, D, Taylor, CK, Abel, PW, Hulce, MR Comeptitive and irreversible antagonists of CGRP, 2006
  • Smith, D, Taylor, CK, Abel, PW, Hulce, MR Comeptitive and irreversible antagonists of CGRP, 2006
  • Taylor CK, Smith DD, Abel PW: Irreversible antagonist of calcitonin gene related peptide, 2005
  • Smith, D, Taylor, CK, Abel, PW: Pharmacological Characterization of Irreversible antagonists of Calcitonin Gene Related Peptide Receptors. American Peptide Symposium., 2004
  • Gordon Conference - 2004. Synthesis of putative irreversible CGRP receptor antagonists., 2004
  • Gordon Conference Submandublar gland muscarinic receptors in a mouse ACHE knockout model. F. Dowd, 2002
  • Use of Calcitonin gene related peptide antagonists to characterize CGRP receptors. D. Smith Gordon Conference - Chemistry and Biology of Peptides, 2002
  • Nebraska Physiological Society - CGRP receptor signaling pathways, 2001
  • EB 2001 CGRP receptor signaling pathways, 2001
  • "Subtypes of alpha-1 adrenergic receptors", 2001
  • Midwest student research Forum - Chris Hague Alpha 1 receptors in BIAA, 2001
  • EB 2001 Age related changes is alpha-1 Adrenergic receptors, 2001
  • Midwest student research forum Boyd CGRP receptor signaling pathways, 2001
  • "The atypical alpha-1 adrenergic receptor", 2001

Awards and Honors

  • PEPTIDE ANTAGONISTS OF CGRP SUPERFAMILY AND METHODS OF USE (Patent No: 6,756,205 B2), 2004
  • PEPTIDE ANTAGONISTS OF CGRP-RECEPTOR SUPERFAMILY AND METHOD OF USE (Patent No: 6268474), 2001
  • PEPTIDE ANTAGONISTS OF CGRP-RECEPTOR SUPERFAMILY AND METHODS OF USE. (Patent No: 09/813,345), 2001