Laura A. Hansen, PhD
Laura A. Hansen, PhD

Laura A. Hansen, PhD

Professor
Director, CU Histology Core Facility
School of Medicine

Academic Appointments

Department

  • Biomedical Sciences

Position

  • Professor

Education

  • Iowa State University,B.S.-Biochem,1981-1986
  • Duke University,Masters-Env. Mgmt,1986-1988
  • North Carolina State University,Ph.D. - Toxicology,1986-1988

Publications and Presentations

Articles

  • 1.   Al-Matouq, J., Holmes, T.R., Hammiller, B., Tran, N., Holmes, M., Freeman, S.C., and Hansen, L.A. Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth. Cancer Letters, in review, 2017., Cancer Letter, 2017
  • Hammiller, B., Karuturi, B.V.K., Miller, C., Holmes, M., Labhasetwar, V., Madsen, G., and Hansen, L.A. Delivery of antioxidant enzymes for prevention of ultraviolet irradiation-induced epidermal damage. PMID 28793966. doi: 10.1016/j.jdermsci.2017.07.015, 2017, Journal of Dermatological Science, 2017
  • Bichsel, K.J., Hammiller, B., Trempus, C.S., Li, Y., Hansen, L.A. The epidermal growth factor receptor decreases Stathmin 1 levels and triggers catagen entry in the mouse. , Experimental Dermatology, 25(4), 175-81, 2016
  • Hammiller, B.O., El-Abaseri, T.B., Dlugosz, A.A., and Hansen, L.A. A method for the immortalization of newborn mouse skin keratinocytes. PMID: 24798404, Frontiers in Oncology, 5, 177, 2015
  • Rao, V.H., K. Vogel, J.K. Yanagida, N. Marwaha, A. Kandel, C. Trempus, S.K. Repertinger, and L.A. Hansen. Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression. doi: 10.1002/mc.22171,, Molecular Carcinogenesis, 54(10) , 1026-36, 2015
  • L.A. Hansen Basal cell carcinoma in Reference Module in Biomedical Sciences, Elsevier, 2015
  • Hansen, L.A. Skin cancer. Reference Module for Biomedical Sciences. doi: 10.1016/B978-0-12-801238-3.05303-4, Elsevier, 2015
  • Squamous Cell Carcinoma Reference Module in Biomedical Sciences.
    Hansen, L.A.
     doi: 10.1016/B978-0-12-801238-3.05309-5, Elsevier, 2015
  • Shirley SH, Hammiller B, Hansen LA, Crysup B, Hudson LG, Kusewitt DF Role of the epidermal growth factor receptor in ultraviolet radiation induction of Snail family transcription factors Role of the epidermal growth factor receptor in ultraviolet radiation induction of Snail family transcription factors., Journal of Dermatological Science, 76(2), 149-151, 2014
  • L.A. Hansen Mycosis Fungoides in Reference Module in Biomedical Sciences. Elseview, Elsevier, 2014
  • Melanoma. Reference Module in Biomedical Sciences. Elsevier.
    Hansen, L.A.  doi: 10.1016/B978-0-12-801238-3.05138-2, Elsevier, 2014
  • Bichsel, K., N. Gogia, T. Malouff, E. Forney, and L.A. Hansen. Genetic deletion of Egfr results in resistance to cyclophosphamide-induced alopecia in mouse skin., PLoS One, 8(7), e69368, 2013
  • T.B. El-Abaseri, B. Hammiller, S.K. Repertinger-Fisher, and L.A. Hansen. The epidermal growth factor receptor increase cytokine production and cutaneous inflammation in response to ultraviolet irradiation, ISRN Dermatology, 1-11, 2013
  • Yanagida, J., Hammiller, B., Behrens, M., Al-Matouq, J., Trempus, C.S., Repertinger, S., and Hansen, L.A. Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A deficient skin, Carcinogenesis, 1754-61, 2012
  • Rao, V.H., Kandel, A., Lynch, D., Pena, Z., Marwaha, N., Deng, C., Watson, P., and Hansen, L.A. A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion, Oncogene, 31(33), 2888-98, 2012
  • Maklad, A., Conway, M., and Hansen, L.A. Development of innervation to maxillary whiskers in mice, Anatomical Record, 293(9), 1553-67, 2012
  • Repertinger, S.K., Madson, J.G., Bichsel, k.J., and Hansen, L.A. The epidermal growth factor receptor in normal and neoplastic epithelia in Signaling Pathways in Squamous Cancer, Van Waes and Glick, ed.s, Springer Publishing, 2010
  • Madson, J.G., Lynch, D.T., Svoboda, J., Ophardt, R., Yanagida, J., Putta, S.K., Bowles, A., Trempus, C.S., Tennant, R.W., and Hansen, L.A. Erbb2 suppresses DNA damage-induced checkpoint activation and UV-induced mouse skin tumorigenesis, Americal Journal of Pathology, 174(6), 2357-66, 2009
  • Virador, V.M., Flores-Obando, R.E., Berry, A., Patel, R., Zakhari, J., Lo, Y-C., Strain, K., Anders, J., Cataisson, C., Hansen, L.A., and Yuspa, S.H. The human prommyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis, Molecular Carcinogenesis, 48(7), 599-609, 2009
  • Maklad, A., Nicolai, J., Bichsel, J.J., Lee, T-C., Threadgill, D.W., and Hnasen, L.A. The epidermal growth factor receptor is required for proper innervation to the skin, Journal of Investigative Dermatology, 129(3), 690-9, 2009
  • Beisel, K., Hansen, L, Soukup, Gl, and Fritzsch, B. Regenerating cochlear hair cells: quo vadis stem cell, Cell and Tissue Research, 333(3), 373-9, 2008
  • Lynch, D., Svoboda, J., Putta, S., Hofland, H.E.J., Chern, W.H.,and Hansen, L.A. Mouse skin models for carcinogenic hazard identificaiton: utilities and challenges, Toxicological Pathology, 35, 853-64, 2007
  • El-Abaseri, T.B., and Hansen, L.A. EGFR activation and ultraviolet light induced skin carcinogenesis, Journal of Biomedicine and Biotechnology, 2007(3), 97939, 2007
  • Madson, J.G. and Hansen, L.A. Multiple mechanisms of Erbb2 action in ultraviolet irradiated skin, Molecular Carcinogenesis, 46(8), 624-628, 2007
  • Morris, J.K., Maklad, A., Hansen, L., Feng, F., Sorenson, C., Lee, K-F., Macklin, W., and Fritzsch, B. A disorganized innervation of the inner ear persists in the absence of ErbB2, Brain Res, 1091, 186-99, 2006
  • Madson, J.G., Lynch, D.T., Tinkum, K.L., Putta, S.K., and Hansen, L.A. Erbb2 regulates inflammation and proliferation in the skin following ultraviolet irradiation, American Journal of Pathology, 169(4), 1402, 2006
  • El-Abaseri, T.B., Putta, S., and Hansen, L.A. Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor, Carcinogenesis, 27(2), 225-231, 2006
  • Khan GA, Bhattacharya G, Mailander PC, Meza JL, Hansen LA, Chakravarti D. Related Articles, Links Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,l]pyrene-treated early preneoplastic SENCAR mouse skin., Journal of Investigative Dermatology, 125(3), 567-74, 2005
  • Fuhrman, J., Shafer, L., Repertinger, S., Chan, T., and Hansen, L.A. Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice, Toxicological Pathology, 33(6), 623-630, 2005
  • , Cancer Research, 65(9), 3958-3965, 2005
  • Maklad, A., B.Fritzsch, and L.A.Hansen. Innervation of the maxillary vibrissae in mice: anterograde and retrograde tract tracing. Cell and Tissue Research, Cell and Tissue Research, 315, 167-180, 2004
  • Wei, S.-J., C.S. Trempus, R.C. Ali, L.A. Hansen, and R.W. Tennant. TPA and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells., J Biol Chem, 279(7), 5993-6004, 2004
  • Maklad, A., B. Fritzsch, and L.A. Hansen, Cell and Tissue Research, 315, 167-180, 2004
  • Hansen, L.A. Skin Cancer in xPharm. Elsevier Science, Inc., Not Applicable, 2004
  • Hansen, L.A. Mycosis Fungoides in xPharm. Elsevier Science, Inc., Not Applicable, 2004
  • Hansen, L.A. Basal cell carcinoma, in xPharm. Elsevier Science, Inc., Not Applicable, 2004
  • Hansen, L.A. Melanoma, in xPharm. Elsevier Science, Inc., Not Applicable, 2004
  • Hansen, L.A. Squamous cell carcinoma, in xPharm. Elsevier Science, Inc., Not Applicable, 2004
  • Repertinger, S., E. Campagnaro, T. El-Abaseri, J. Fuhrman, S.H. Yuspa, and L.A. Hansen, In press, Journal of Investigative Dermatology, 2004
  • Seker, H., Rubbi., C., Linke, S.P., Bowman, E.D., Garfield, S., Hansen, L., Milner, J., and Harris, C.C. DNA damage induces p53 dependent nuclear trafficking of PML. S, Oncogene, 22, 1620-28, 2003
  • Hansen,L.A., D.Brown, V.Virador, K.Strain, B.Dancheck, T.Tanaka, F.Andreola, R.Rountree, J.M.Arbeit, L.M.De Luca, S.Kogan, and S.H.Yuspa. A PMLRARalpha transgene results in a retinoid deficient phenotype associated with enhanced susceptibility to skin tumorigenesis. In press in Cancer Research, Cancer Research, 63, 5257-5265, 2003
  • Hansen, L.A., D. Brown, V. Virador, T.Tanaka, F. Andreola, K, Strain, B. Dancheck, R. Riley, J.M. Arbeit, L.M. De Luca, S. Kogan, and S.H. Yuspa, Cancer Research, 63, 5257-5265, 2003
  • Seker, H., Rubbi, C., Linke, S.P., Bowman, E.D., Garfield, S., Hansen, L., Borden, K.L.B., Milner, J., and Harris, C.C., Oncogene, 22, 1620-1628, 2003
  • Woodworth, CD, Gaiotti, D, Michael, E, Hansen, L, Nees, M Title: Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes., Cancer Research, 60(16), 4397-4402, 2000
  • Hansen LA, Woodson RL 2nd, Holbus S, Strain K, Lo YC, Yuspa SH Title: The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors., Cancer Research, 60(13), 3328-3332, 2000
  • Hansen LA, Sigman CC, Andreola F, Ross SA, Kelloff GJ, De Luca LM, Carcinogenesis, 21(7), 1271-9, 2000
  • Hansen, L.A. Squamous cell carcinoma. xPharm (in press); Eds.: David B. Bylund and S.J. Enna; Elsevier Science, Inc.
  • Hansen, L.A. Skin cancer. xPharm (in press); Eds.: David B. Bylund and S.J. Enna; Elsevier Science, Inc.
  • Fritzsch, B., Beisel, K.W., and Hansen, L.A. The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration!, Bioessays, 28, 1181-93

Publications

  • Abstract, Targeting of estrogen receptor-alpha36 decreases skin cancer stem cells and increase differentiation. Holmes, M., Pham, D., Nicholson, Y., Hammiller, B., Wang, T, Wang, Z-Y, and Hansen, L.A. Creighton University Research Day, 2017
  • Abstract, EPIDERMAL GROWTH FACTOR RECEPTOR REGULATION OF STATHMIN1 IN MOUSE SKIN CANCER. Aileen Park, Brianna Hammiller, Carol Trempus, Laura A. Hansen, Midwest Student Biomedical Research Forum, 2017
  • EFFICACY OF PRO-NPTM ANTIOXIDANT DELIVERY FOR PREVENTION OF ULTRAVIOLET IRRADIATION-INDUCED DAMAGE IN MOUSE SKIN
    Sean Smith, Yawah Nicholson, Brianna Hammiller, Christina Miller, Tammy Wang, Gary Madsen, Laura A. Hansen, Midwest Student Biomedical Research Forum, 2017
  • CYTOPLASMIC ACCUMULATION OF CDC25A ENHANCES CELL SURVIVAL IN CUTANEOUS SQUAMOUS CELL CARCINOMA, Holmes, T., Hansen., L.A. MSBRF, 2017, 2017
  • Tyler Bendrick, Thomas Holmes, and Laura Hansen. CDC25A inhibition in squamous cell carcinoma. Ferlich Poster Symposium, 2016
  • Thomas Holmes, Brianna Hammiller, and Laura A. Hansen, CDC25A and Expoertins in cutaneous SCC. Creighton University Research Day, 2016
  • Cara S. Franey, Thomas Holmes, Brianna Hammiller, Yawah Nicholson, Laura A. Hansen. EFFECT OF CDC25A OR 14-3-3 INHIBITION ON SQUAMOUS CELL CARCINOMA, Midwest Student Biomedical Research Forum, 2016
  • Thesis completed by my M.S. advisee John Lehman entitled ADAM12 in head and neck cancer, 2015
  • Cassidy Plunkett, Brianna Hammiller, Kyle Bichsel, Jessica Gaulter, and Laura A. Hansen Epidermal growth factor receptor regulation of Stathmin 1 in mouse skin cancer, Creighton University Honors Day, 2015
  • Timothy Malouff, Kyle J. Bichsel, Yanhua Li, Brianna Hammiller, Carol Trempus, Laura A. Hansen EGFR AND STATHMIN1 IN PROGRESSION THROUGH THE HAIR CYCLE, Midwest Student Biomedical Research Forum, 2015
  • Lauren Nicola; Nicholas Tran; Jenan Al-Matouq; Brianna Hammiller; and Laura A. Hansen CYTOPLASMIC LOCALIZATION OF 14-3-3 IS ASSOCIATED WITH SUPPRESSION OF CELL DEATH IN CUTANEOUS SQUAMOUS CELL CARCINOMA, Midwest Student Biomedical Research Forum, 2015
  • Dissertation by my Ph.D. advisee Jenan Al-Matouq entitled Role of CDC25 phosphatases in non-melanoma skin cancer. 2014, 2014
  • Inhibition of erbB2 suppresses UV-induced skin tumorigenesis through a mechanism independent of EGFR Justin G. Madson1, Gregory S. Ramirez1, Carol Trempus2, Raymond W. Tennant2, and Laura A. Hansen11 Creighton University, Omaha, NE and 2National Institute for Environmental Health Sciences, Research Triangle Park, NC, AACR Proceedings Apoptosis and Cancer, 2006
  • EGFR and erbB2 receptor tyrosine kinase targeted siRNA decreases receptor expression, Creighton University Honors Program Symposium, 2005
  • Epidermal growth factor receptor activation of MAP kinases regulates progression through multiple cell cycle phases, American Association for Cancer Research, 2005
  • Regulation of gene expression by erbB2 in response to ultraviolet irradiation of the skin, American Association for Cancer Research, 2005
  • Chemoprevention of ultraviolet light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor, Montagna Symposium for Cancer Research, 2004
  • Annual meeting, Inhibition of EGFR suppresses ultraviolet irradiation-induced tumorigenesis through multiple mechanisms, American Association for Cancer Research, 2004
  • Abstract entitled: The epidermal growth factor receptor regulates cutaneous proliferation through ERK and p38 MAP kinase pathways, Midwest Student Biomedical Research Forum, 2004
  • Virador, V.M., Hansen, L.A., Flores-Obando, Patel, R., Strain, K., Lo, Y.-C., Berry, A., and Yuspa, S.H., Not Applicable, 2003
  • El-Abaseri, T. and Hansen, L.A., Proceedings of the AACR, 2003
  • Lie, M., Patel, S., and Hansen, L.A., Not Applicable, 2003
  • El-Abaseri, T., and Hansen, L.A., Proceedings / Workshops, 2003
  • The epidermal growth facotr receptor suppresses ultraviolet light-induced cell cycle arrest and apoptosis in keratinocytes. Laura A. Hansen, Sanjay Patel, Mercy Ossa-bucle, Laura Marsh, Taghrid El-Abaseri, AACR Proceedings Apoptosis and Cancer, A53, 2002

General

Presentations

  • Invited Speaker, Title: Novel Targets for Skin Carcinogenesis, LB595 Cancer and Smoking-related Diseases Program, 2017
  • Invited Speaker, Title: Estrogen Receptor alpha 36 in skin cancer progression, 2017
  • Invited speaker, Title: Relocalized CDC25A suppresses cell death in cutaneous squamous cell carcinoma, The 12th International Skin Carcinogenesis Conference., 2017
  • Invited Speaker, Title: Mechanisms of skin cancer development and progression, Department of Pharmacology, CUSOM, 2016
  • Seminar, Role of CDC25C phosphatase in non-melanoma skin cancer, LB595, 2015
  • Cassidy Plunkett, Brianna Hammiller, Kyle Bichsel, Jessica Gaulter, and Laura A. Hansen Epidermal growth factor receptor regulation of Stathmin 1 in mouse skin cancer, Creighton University Honors Day, 2015
  • Timothy Malouff, Kyle J. Bichsel, Yanhua Li, Brianna Hammiller, Carol Trempus, Laura A. Hansen EGFR AND STATHMIN1 IN PROGRESSION THROUGH THE HAIR CYCLE Midwest Student Biomedical Research Forum, 2015 *Third place poster presentation., 2015
  • Lauren Nicola; Nicholas Tran; Jenan Al-Matouq; Brianna Hammiller; and Laura A. Hansen CYTOPLASMIC LOCALIZATION OF 14-3-3 IS ASSOCIATED WITH SUPPRESSION OF CELL DEATH IN CUTANEOUS SQUAMOUS CELL CARCINOMA Midwest Student Biomedical Research Forum, 2015
  • Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: 14-3-3 and CDC25, CU Department of Biomedical Sciences,, 2014
  • Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: ADAM12 and CDC25 phosphatases, Kansas State University, 2014
  • Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Presentation at the American Association for Cancer Research Meeting, May 2014, 2014
  • Hansen, L.A. Novel biomarkers and therapeutic targets for nonmelanoma skin cancer. Oral presentation for LB595, April 2014, 2014
  • Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Poster presentation at the Midwest Biomedical Student Research Forum, February, 2014, 2014
  • Platform presentation at the Society of Toxicology annual meeting in Baltimore MD, 2009
  • Invited speaker at Pennsylvania State University, College Station, PA, 2008
  • Invited seminar at UNL, Epidermal growth factor receptor: surprises from the skin, 2008
  • Invited speaker, VA, Omaha, NE, 2008
  • Erbb2 and ultraviolet irradiation in skin carcinogenesis, University of Nebraska, Lincoln, NE, 2006
  • Inhibition of erbB2 suppresses UV-induced skin tumorigenesis through a mechanism independent of EGFR, American Association for Cancer Research, 2006
  • The role of Erbb2 in the response of the skin to UV, Nebraska Center for Cellular Signaling, 2006
  • Seminar title: The role of erbB2 in UV-induced skin carcinogenesis., 2005
  • Seminar title: EGFR in cutaneous innervation, 2004
  • EGFR in peripheral nervous system innervation, 2004
  • The epidermal growth factor receptor in cancer biology, 2003
  • Invited speaker, Growth factor receptors, sunlight, and skin cancer, National Institute for Environmental Health Sciences, Research Triangle Park, NC, 2003
  • Invited speaker at the Great Plains States Society for Molecular Biology and Genetics annual meeting, 2003
  • Invited speaker, 4th Annual Steve Schiff Center for Skin Cancer Research Symposium, Title: The epidermal growth factor receptor regulates cell cycling and cell death during skin carcinogenesis, 2002
  • Invited speaker, VA hospital, Title: The epidermal growth factor receptor regulates cell death and division during skin carcinogenesis, 2001
  • Invited speaker, 3rd Midwest Regional AAAS Meeting, Title: Regulation of cell growth and death by the epidermal growth factor receptor during skin carcinogenesis, 2001
  • Invited speaker, Department of Pharmacology Seminar Series, UNMC, Title: Regulation of cutaneous cell division and cell death by the epidermal growth factor receptor, 2001
  • Panel discussion member, National Institute for Environmental Health Sciences Science Forum Topic: Searching for Faculty Positions, A Discussion by TIP Grantees, 2001
  • A PMLRARalpha transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis, poster presentation at the American Association for Cancer Research annual meeting, 2001
  • UNMC Department of Cell Biology, seminar, Title: Epidermal growth factor receptor mediated maintenance of cell proliferation in skin tumorigenesis., 2001
  • 3/5/2001 UNMC Department of Biochemistry, seminar, Regulation of cell division and differentiation by the epidermal growth factor receptor in the skin., 2001

Research and Scholarship

Grant Funding Received

  • LB595 Program Project Title: Molecular Mechanisms and Novel Targets in Cancer. Project PI: Novel therapeutic targets for nonmelanoma skin cancer Dates: 7/1/14-6/30/19 Award: $2,000,000 direct over 5 years, $500,000 for my project
  • LB595 Pilot Project Title: ERalpha36 and skin cancer progression.
  • State of NE-LB595 Title: Cancer and smoking-related diseases seminar series.
  • CURAS Project Title: Cytoplasmic CDC25A localization and suppression of apoptosis in cancer cells.
  • INBRE PI: M. Nichols (Co-I: Hansen) Title: Metabolic imaging of disease progression in skin cancer by FLIM
  • ProTransit Nanotherapy Project Title: The Protective Efficacy of PLGA Nanoparticles Encapsulating Antioxidant Enzymes against UV Radiation Exposure
  • State of NE-LB506
  • NIH RO1 ES015585 Title: Mechanisms of UV-induced skin carcinogenesis
  • State of NE-LB595 Title: Molecular and cellular mechanisms of carcinogenesis program
  • State of NE-LB595 Title: Cancer and smoking-related diseases seminar series
  • NE-LB595 Pilot Project Title: ADAM12 and head and neck cancer progression
  • NE-LB595 Pilot Project Title: Oral carcinogenesis and ADAM12
  • NIH ARRA Title: Summer student supplement to RO1
  • The Dobleman Institute for Head and Neck Cancer Research Title: Matching funds for ADAM12 and head and neck cancer progression
  • State of NE-LB506 Title: HER2 and the response to chemotherapeutic agents in SCC
  • State of NE-LB692 Title: Does defective catagen entry trigger folliculitis in Egfr mutant skin?
  • State of NE-LB595 Title: Mechanisms of cell cycle regulation by Erbb2
  • Health Future Foundation Scholar Award Title: Regulation of cell cycle progression by HER2 in mammary cancer cells
  • State of NE-LB692 Title: The role of erbB2 in PNS, skin, and ear as revealed by conditional mutation analysis
  • NIH Center of Biomedical Research Excellence (COBRE) (PI: Wheelock) Project PI 50% effort My project title: erbB2 in UV-induced skin carcinogenesis National Institutes of Health Award: $686,821 direct costs for my portion, $276,599 indirect (total award approximately $10,000,000 over five years)
  • Connetics Corporation Title: Mechanisms of tumorigenesis in Tg.AC mice
  • Connetics Corporation Title: Analysis of the effects of topically applied agents to Tg.AC skin
  • NIH RO1 (PI: Kusewitt) Collaborating investigator Title: Modulators of EMT in skin carcinogenesis
  • NIH COBRE (PI: Smith) Project Principal Investigator 40% effort Title: The molecular biology of neurosensory development (My individual project title is “The role of EGFR in sensory development.)
  • NIH K-22 Award ES00365-01 Title: The role of EGFR in UV-induced skin carcinogenesis
  • Macrochem Corporation Title: Mechanisms of SEPA-induced carcinogenesis in Tg.AC mice
  • NIH SBIR Title: Developing Pro-NP for skin cancer prevention
  • NIH R01 Title: Targeting CDC25A for skin cancer prevention
  • LB595 Pilot Project Title: Flower-mediated cell competition in skin cancer

Awards and Honors

  • First Place Prize for Graduate Student Poster, Creighton University Research Day, 2017
  • Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum, 2015
  • Provisional-METHOD OF SUPPRESSING UV-INDUCED SKIN TUMORIGENESIS (Patent No: 60/848108), 2006
  • Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum, 2006
  • Society of Investigative Dermatology Eugene M. Farber Endowment Award, 2004